Scientific Journal of KubSAU

Polythematic online scientific journal
of Kuban State Agrarian University
ISSN 1990-4665
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Name

Koba I. S.

Scholastic degree

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Honorary rank

Organization, job position

Krasnodar Scientific Research Institute of Veterinary
   

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Articles count: 7

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186 kb

FACTORS CONTRIBUTING TO THE EMERGENCE OF FUNCTIONAL DISORDERS OF BIRTH-GENITAL APPARATUS AT COWS

abstract 1211607113 issue 121 pp. 1818 – 1827 30.09.2016 ru 74
ЖИВОТНОВОДСТВО, КРУПНЫЙ РОГАТЫЙ СКОТ, ДИСФУНКЦИЯ ЯИЧНИКОВ, ЭНДОМЕТРИТ, БЕСПЛОДИЕ, СУБИНВОЛЮЦИЯ МАТКИ, ПОЛОВОЙ ЦИКЛ, ПЕРСИСТИРУЮЩЕЕ ЖЕЛТОЕ ТЕЛО, КИСТА ЯИЧНИКОВ, ГОРМОНЫ
517 kb

PHARMACO-TOXICOLOGICAL EVALUATION OF TISSUE DRUG MICROBIOSTIM

abstract 0400806005 issue 40 pp. 35 – 47 25.06.2008 ru 2775
Рharmaco-toxicological evaluation of drug Microbiostim, not possessing toxic and allegic action, normalizing biochemical and hematological blood indexes of cows and decreasing multiple of introduction and expense of drug under combinative use with endometrogan-T, increasing on 10% the therapeutic efficiency and decreasing length of sterility on 20,9 days with comparison with PDS has been given in this article.
143 kb

PRECLINICAL STUDIES OF PHARMACOLOGICAL PROPERTIES OF A NEW DRUG URITOSOM FOR THE TREATMENT AND PREVENTION DISEASES OF GENITOURINARY SYSTEM

abstract 1241610056 issue 124 pp. 852 – 861 30.12.2016 ru 170
In this study, the authors have defined the acute, subchronic and chronic toxicity of Uritosom preparation, and also its skin-irritating and sensitizing action. The studies that determined the acute toxicity of the drug Uritosom found that remedy which intended for the treatment and prevention of diseases of the genitourinary system with internal method of appointment during the entire observation period did not cause the death and acute toxicity in laboratory animals. In the study of subchronic and chronic toxicity of the drug Uritosom throughout the observation period in both experimental groups death and acute intoxication in animals not registered, also there were no negative phenomena in behavior, reflexes were saved. Consequently, the preparation according to the degree of impact on the body of warm-blooded animals refers to low-hazard substances (4th class of hazard according to GOST 12.1.007-76). Study of the irritant action of Uritosom preparation was carried out in two series of experiments. In the first series of experiments was determined irritating action by conjunctival swab sampling method, in the second - by skin application. The study of the sensitizing action of the drug was determined by the method of maximum sensitizing effects. The authors have found that the preparation has no irritating and sensitizing effect on the tissue in its application zone. On this basis, Uritosom preparation at different ways of application is low-toxic and it can be recommended for clinical research
106 kb

PROPHYLACTIC EFFECTIVENESS OF DRUG MICROBIOSTIM UNDER COMPLICATED CALVING AND POSTNATAL PERIOD AT COWS

abstract 0400806004 issue 40 pp. 29 – 34 25.06.2008 ru 2704
Drug Microbiostim as highly effective means of prophylaxis of obstetric-gynecologic pathology at cows was analyzed in this paper.
92 kb

STIMULATING ACTION OF DRUG MICROBIOSTIM UNDER HYPO FUNCTION OF OVARIES AT COWS

abstract 0400806003 issue 40 pp. 24 – 28 25.06.2008 ru 2505
Stimulating action of drug Microbiostim, worked out in Krasnodar scientific research veterinary institute and using for treatment and prophylaxis of hypo function of ovaries at cows and calves was analyzed in this article.
266 kb

TREATMENT OF CHRONIC ENDOMETRITIS WITH THE NEW DRUG FLORINAZOL

abstract 1231609070 issue 123 pp. 1011 – 1025 30.11.2016 ru 181
In the article data on spread of chronic endometritises at cows are provided. The microflora range, being in genitals of patients with a chronic endometritis of cows is determined. We have developed a new drug called Florinazol and we also determined his antimicrobic and fungicide activity. Researches on determination of acute and chronic toxicity, and also irritant action on a mucous membrane of a uterus and a vagina are conducted. Researches on studying of influence of Florinazol on blood biochemistry at rabbits are conducted. The optimum therapeutic dose and frequency rate of its introduction is determined. By results of researches it is established that 24,8% of the cows containing on a farm with loose housing content and 10,6% of cows on a farm with fastened content have a chronic endometritis. At the same time in uterus content in 84,3% of cases isolated associations of bacteria and mushrooms in 65,2%, in 34,8% - monocultures of microorganisms. Offered by us means the danger class belongs to substances lowdangerous by the 4th. Doesn't possess irritant action, doesn't exert a negative impact on blood biochemistry, and also has outstanding therapeutic performance of 90% in case of its application in a dose of 100 ml intra-vaginal at an interval of 48 hours
284 kb

USE OF FLUCONAZOLE FOR TREATMENT OF CHRONIC ENDOMETRITIS AT COWS

abstract 1241610057 issue 124 pp. 862 – 874 30.12.2016 ru 165
That article is of interest to practicing veterinarians. Currently, the biggest obstacle in the development of dairy farming is infertility at cows, which is caused by the presence of diseases of the reproductive organs, most of which is occupied by acute and chronic endometritis. The frequency of occurrence of chronic endometritis at cows reaches high levels, from 10 to 66.3%, averaging 14%. One of the direct causes of chronic endometritis is association of pathogenic and opportunistic microorganisms and fungi. Many chemotherapeutic agents which are designed for prophylaxis and treatment of acute postpartum endometritis do not give a high therapeutic effect in the treatment of chronic endometritis or amount and frequency of application drugs is very high. Analyzing the data, the authors developed a new drug which has fungicidal and antibacterial actions - Florinazol. The experiments showed that the use the Florinazol preparation in combination with myotropic, pathogenetic and vitamin preparations gives 90% of therapeutic efficiency, while the frequency of administration of the drug was on average 3 fold, and the duration of treatment was 5 days
.