Scientific Journal of KubSAU

Polythematic online scientific journal
of Kuban State Agrarian University
ISSN 1990-4665
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Name

Ogban Gabriel Iyam

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Kuban State University
   

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Articles count: 1

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MATHEMATICAL MODEL OF THE DYNAMICS OF HIV INFECTION WITHOUT TREATMENT

abstract 1101506038 issue 110 pp. 562 – 578 30.06.2015 ru 1033
This article discusses the mathematical and numerical modeling of the immune system of the course of HIV infection without treatment. Presently a significant number of scientific papers are devoted to the study of this problem. However, HIV infection is highly volatile and there is no effective drug, in that HIV has the ability to mutate and reproduce itself in the presence of chemical substances that are meant to inhibit or destroy it. The mathematical models used in this paper are conceptual and exploratory in nature. The proposed mathematical model allow us to obtain a complete description of the dynamics of HIV infection, and also an understanding of the progression to AIDS. Thus, the results of the numerical solution of differential equations in this work show that: the disease develops, and at low concentration of the virus, a certain level of stability does not depend on the initial concentration of infestation. In the absence of treatment, for interesting competition between virus and the loss of virus caused by immune response should be strictly greater than the rate of multiplication of the virus in the blood; the reproduction rate of the uninfected cells should be stricly greater than the mortality rate of the uninfected cells
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