Name
Demidova Alexandra Alexandrovna
Scholastic degree
•
Academic rank
associated professor
Honorary rank
—
Organization, job position
Rostov state medical university
Web site url
—
Articles count: 1
While studying the content of hypoxia-inducible factor
1-alpha and vascular endothelial growth factor in the
tumor tissue, oral fluid and peripheral blood of 141
patients with oral mucosa cancer T1-3N0-2M0, it was
shown that the development of purulent inflammatory
postoperative complications in patients with oral
mucosa cancer is associated with an increased
expression of HIF-1α in the tissue and its translocation
from the cytoplasm to the nucleus, activation of the
neoangiogenesis processes. It is informative to
determine HIF-1α factor in the blood serum, which,
for further development, can be used as a non-invasive
diagnostic marker to predict the postoperative course
in this category of patients