Scientific Journal of KubSAU

Polythematic online scientific journal
of Kuban State Agrarian University
ISSN 1990-4665
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THE EFFECT OF NON-DRUG TREATEMENT OF CLIMACTERIC DISORDERS ON THE GASTROINTESTINAL TRACT IN FEMALE PATIENTS WITH METABOLIC SYNDROME

abstract 1161602104 issue 116 pp. 1661 – 1670 29.02.2016 ru 0
The aim of the research was to assess the effect of nondrug correction methods of climacteric disorders on the digestive system in patients with metabolic syndrome. 330 women aged 45-50 with the diagnosed metabolic syndrome were examined. Three comparable groups were formed with 110 female patients in each group. In the main group the methods of the nondrug treatment (diet therapy, psychotherapy, physical therapy, exercise therapy) and the vitamin-mineral treatment were combined. In the first control group only the non-drug treatment was used. In the second control group only the vitamin-mineral treatment was used. The female patients’ complaints and the biochemical profile parameters were assessed before the treatment and six months after the treatment. Ultrasound scanning of the abdominal cavity, fibrogastroduodenoscopy and videocolonoscopy were carried out. The results of the study are as follows. In all patients the digestive tract problems were diagnosed at the beginning of the research. Moreover, combined damages were noticedin most of the patients. The main group demonstrated the most pronounced positive dynamic according to the subjective evaluation of the symptoms as to the gastrointestinal tract, as well as according to the parameters of the carbohydrate and fat metabolism. We may conclude that the complex non-drug correction of climacteric disorders in female patients with metabolic syndrome, directed on the increase of the adaptation abilities of thewomen’s organism, the normalization of all kinds of metabolism and of the endocrine profile, has the most important positive effect on the organs of the gastrointestinal tract. This, in its turn, well coordinates all the kinds of metabolism
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THE RANGE OF THE CARDIOPULMONARY SYNCHRONISM AT VARYING DEPTHS OF THE HIGH RATE RESPIRATION DEPENDING ON THE PERSONALITY TYPE

abstract 1151601029 issue 115 pp. 435 – 454 27.01.2016 ru 286
In this article we have listed the data concerning the influence of the respiration depth on the parameters of the cardiopulmonary synchronism depending on the personality type
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FINDING THE CENTER OF THE NEURONAL ACTIVITY RELATED TO THE HEART RHYTHM IN THE FROG MEDULLA OBLONGATA

abstract 1151601027 issue 115 pp. 417 – 425 27.01.2016 ru 289
Via the method of visualizing the excitation in the high frequency field there were discovered the efferent signals in the frog medulla oblongata, which were related to the heart rhythm
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THE ASSESSMENT OF THREATENED MISCARRIAGE USING REGULATIONADAPTIVE STATUS

abstract 1151601031 issue 115 pp. 469 – 479 27.01.2016 ru 290
The index definition of regulatory-adaptive status in women with the threat of termination of pregnancy in the first trimester is a highly predictor of pregnancy outcome and should be used in obstetric hospitals and antenatal clinics
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PREDICTION OF ADAPTATION OF PATIENTS TO FIXED TEETH USING REGULATORYADAPTIVE STATUS RATE

abstract 1151601030 issue 115 pp. 455 – 468 27.01.2016 ru 341
Using the of rate regulatory-adaptive status we can make a prediction for adaptation of patients to fixed teeth
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SELECTION OF FETAL CELLS CIRCULATING IN MATERNAL BLOOD FOR NONINVASIVE PRENATAL DIAGNOSIS

abstract 1151601082 issue 115 pp. 1288 – 1309 27.01.2016 ru 375
Trophoblast cells circulating in maternal blood may serve as potential sources of genetic information for screening in obstetric practice approaches to noninvasive prenatal diagnosis. The material for the study was whole blood of pregnant women of gestational ages of 8-12 weeks in a volume of 10 ml. stabilized with heparin. Enrichment was performed by the method of gradient centrifugation and magnetic separation (CD45–) with fluorescent staining negative fractions labeled with antibodies to antigens of trophoblasts (HLA-G, and Trop-2) to conduct flow cytometry and sorting of cells on glass slides. Single cell candidates using laser micro dissection were transferred into a vial for subsequent whole-genome amplification, providing sufficient representativeness of their genome. Fetal origin of the genetic material was confirmed by comparison of alleles of the HLA genes of the parents and cells candidates. It is possible to improve significantly the accuracy and versatility of non-invasive prenatal diagnosis using comparative genomic hybridization using chips (аCGH)
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CHANGE OF THE NEURONAL AFFERENT ACTIVITY IN THE FROG MEDULLA OBLONGATA FOR LEARNING THE HEART VAGO - SYMPATHETIC TRUNK RHYTHM

abstract 1151601028 issue 115 pp. 426 – 434 27.01.2016 ru 382
In the high frequency electric field we have revealed afferent signals in the frog medulla oblongata for learning the heart vago - sympathetic trunk rhythm
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CLINICAL AND MORPHOLOGICAL FACTORS AND PREDICTION PARAMETERS OF CELL CYCLE IN ESOPHAGEAL CANCER

abstract 1241610028 issue 124 pp. 484 – 493 30.12.2016 ru 384
The aim of the study is to compare the traditional clinicopathologic factors and prognosis of cell cycle parameters, such as ploidy, cell cycle kinetics, as well as the study of DNA content in the tumor tissue of patients with esophageal cancer. Cancer of the esophagus - a very aggressive malignant disease, most commonly manifested impaired swallowing. As a rule, this type of cancer pathology is characterized by unfavorable outcome. Ploidy and cell proliferation activity, defined by the content of the DNA of the tumor - synthesizing cells are one of the important indicators of the growth rate of malignancy and prognosis. The study was performed on tumor tissue fragments of the 30 patients operated on for cancer of the esophagus. DNA study - conducted in the open cell material aftercare. DNA cell content was determined by flow cytometry BD FACSCanto II. By studying the DNA-cytometric parameters, we found the prevalence of aneuploid tumors in 66.7%. It was shown that DNAcytometric parameters are independent of gender. Major weight of diploid and aneuploid cell tumors of the esophagus was in G0 / 1 phase of the cell cycle. Comparative analysis of DNA - cytometric parameters and the degree of differentiation of esophageal tumor revealed a prevalence of aneuploid tumors in all the test cases. content distribution pattern of tumor cells was found in the G0 / G1-, G2 + M -, S - phase of the cell cycle at different stages of the disease
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HIFU: PROSPECTS OF APPLICATION IN ONCOUROLOGY

abstract 1221608019 issue 122 pp. 264 – 277 31.10.2016 ru 412
Prostate cancer (PC) is one of the most frequently malignant neoplasms in the worldwide male population. Back in the 90's began a promising noninvasive method of high-intensity focused ultrasound (HIFU) as an alternative to radical prostatectomy for the treatment of localized prostate cancer was used. Information about the destructive histological effect by HIFU has been known since the 1930, however, the clinical implementation of this technology due to the absence at the time visualization capabilities for monitoring during the procedure has been postponed. In this paper, an overview of published data on the HIFU clinical application in prostate cancer as a major, "saving" and focal therapy. Examples of a favorable combination of this method are also provided with pharmacological agents. Based on the analysis of clinical data, we can say that HIFU is a good alternative minimally invasive therapeutic modality for patients with prostate cancer who are not candidates for radical prostatectomy. Applying of HIFU is possible as a treatment option with local recurrence after external radiotherapy, with careful selection of patients is important, depending on prognostic factors
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PATHOLOGY OF CARDIOVASCULAR SYSTEM AT PERSONNEL OF COMMERCIAL FLEET

abstract 1291705003 issue 129 pp. 37 – 46 31.05.2017 ru 473
It is known that there are most widespread the diseases of cardiovascular system among the examined seamen. We have carried out the analysis of distribution of concrete nosological forms of pathology of cardiovascular system and concomitant diseases (gastrointestinal tract, nervous system, ENT organs, the musculoskeletal apparatus and others). Results of preventive screening of the crew personnel performed in 2007–2010 by medical commission of Novorossiysk clinical center of Russia’s Federal Medico-Biological Agency were subject to scientific research. 3352 seamen aged from 18 to 60 years (middle age 27,2+1,3 years), among which 2627 surveyed – personnel of bluewater shipping, 725 surveyed – personnel of domestic shipping have been subjected to studying. The examined contingent is ranged taking into account professional groups. It is revealed that cardiovascular pathology is almost equally widespread in all professional groups of personnel of ships of domestic and blue-water shipping. This pathology occurs at 13,5–21% of the seamen corresponding who had medical examination. The main group of the examined seamen (79–96,7%) belongs to the category «almost healthy» and suitable for work in the sea. Among revealed pathology at seamen, the high specific weight (63– 70%) belongs to diseases of cardiovascular system. Probable intensive work and harmful factors of the ship environment in each of professional groups exert significant negative impact on psychic and somatic health of seamen. Neurocirculator dystonia (hypertensive and cardio types) dominates in structure of cardiovascular pathology registered at seamen of both professional groups. The associated diseases (71–82%) meet more often at persons with hypertension, manifesting forms of atherosclerosis and ischemic disease. In both groups, we have noted the high percent of violations of digestive tract, musculoskeletal apparatus, alimentary and constitutional obesity and eyesight. However, alimentary and constitutional obesity and diseases of musculoskeletal apparatus are most characteristic of the personnel of ships performing long maritime traffic. Obviously, this phenomenon is connected with hypodynamia
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