Study was performed on 12 samples of astrocytic human brain tumors, which differ by the level of malignancy and histological indications. The study was conducted with the method of immunohistochemistry using a commercially available antibody anti-connexin-43 (Cx 43), a prior test of
which was carried out on myocardium tissue of rats (positive control). The study showed that with the increasing of malignant level of astrocytomas, there was marked the decreased level of connexin-43 expression of, which is apparently to be associated with the destruction of intercellular gap junctions in tumor tissue
The results of the questionnaire survey of cadets of
Maritime University, Maritime College and students
who had been given training in the Institution of
Advanced Training are presented. It is revealed that
the level of motivation of ship personnel for first aid
treatment to victims on commercial ships is two times
lower than that of cadets. The conclusion about the
necessity of solution the legal aspects of sailorsparamedics,
working under the Russian flag was made
The article presents an analysis of features of the
organization of special medical and prophylactic
support on commercial ships. First-aid treatment at
poisoning of crews of the most widespread toxic
matter (poisonous gases, oil products, methane,
coolants, and fumigants) has been considered. It is
noted that medical aspects of toxic dangers on the
water transport have to include prevention of the
pathological states of health of seamen, timely medical
support of the ship, early diagnostics of pathological
states, sorting of injured persons and the organization
of first emergency medical aid
The aim of this work: a study of health - social and ethical aspects of health care workers in the framework of the prevention of a healthy lifestyle among youth. To study the level of students' knowledge about HIV prevention and detection of bad habits - drinking, smoking, drug addiction, a study author profiles. We
have used empirical, sociological and statistical methods
The work includes the clinical comparative analysis of ectopic pregnancy’s mortality cases caused by he-morrhagic shock and near miss. Current results contain morphological changes in the adenohypophysis which depend on the amount of hemorrhage and determine the direction of rehabilitation measures in a group of patients who experienced hemorrhage shock
Isolation of fetal cells from the blood of a pregnant
woman is more relevant for receiving the information
of the genome of a fetus and implementation in clinical
practice, non-invasive screening methods for prenatal
diagnosis. The work proposes efficient ways of sorting
trophoblasts circulating in maternal blood for the
diagnosis of fetal aneuploidy in early gestation by
analyzing microsatellite marker of the chromosomes
that most prone to numerical aberrations (13, 18, 21, X
and Y). A set of microsatellite markers allowed to
reveal aneuploidy in three pregnant women, and also
to exclude mosaicism and contamination of samples
with maternal cells. A retrospective analysis of data on
invasive cytogenetic studies (chorionic villus
sampling) confirmed the results of the study
It is known that there are most widespread the
diseases of cardiovascular system among the
examined seamen. We have carried out the analysis
of distribution of concrete nosological forms of
pathology of cardiovascular system and concomitant
diseases (gastrointestinal tract, nervous system, ENT
organs, the musculoskeletal apparatus and others).
Results of preventive screening of the crew
personnel performed in 2007–2010 by medical
commission of Novorossiysk clinical center of
Russia’s Federal Medico-Biological Agency were
subject to scientific research. 3352 seamen aged
from 18 to 60 years (middle age 27,2+1,3 years),
among which 2627 surveyed – personnel of bluewater
shipping, 725 surveyed – personnel of
domestic shipping have been subjected to studying.
The examined contingent is ranged taking into
account professional groups. It is revealed that
cardiovascular pathology is almost equally
widespread in all professional groups of personnel of
ships of domestic and blue-water shipping. This
pathology occurs at 13,5–21% of the seamen
corresponding who had medical examination. The
main group of the examined seamen (79–96,7%)
belongs to the category «almost healthy» and
suitable for work in the sea. Among revealed
pathology at seamen, the high specific weight (63–
70%) belongs to diseases of cardiovascular system. Probable intensive work and harmful factors of the
ship environment in each of professional groups
exert significant negative impact on psychic and
somatic health of seamen. Neurocirculator dystonia
(hypertensive and cardio types) dominates in
structure of cardiovascular pathology registered at
seamen of both professional groups. The associated
diseases (71–82%) meet more often at persons with
hypertension, manifesting forms of atherosclerosis
and ischemic disease. In both groups, we have noted
the high percent of violations of digestive tract,
musculoskeletal apparatus, alimentary and
constitutional obesity and eyesight. However,
alimentary and constitutional obesity and diseases of
musculoskeletal apparatus are most characteristic of
the personnel of ships performing long maritime
traffic. Obviously, this phenomenon is connected
with hypodynamia
Using the of rate regulatory-adaptive status we can
make a prediction for adaptation of patients to fixed
teeth
The problem of rendering of first medical aid to
personnel of commercial ships under the Russian flag
is considered. It is shown that the decision of this
problem in our country is impossible without juridical
aspects of activity of sailors-paramedics, questions of
their training in bases of rendering an emergency aid
and due medical support of the Russian ships. The
emergency elementary aid has to be an integral part of
activity of personnel of ships. Some directions of the
decision of a problem of efficiency of providing such
help to personnel of ships are proposed. Development
of the bill directed to introduction in Russia of
requirements for assistance by paramedics on
commercial ships is necessary
A retrospective immunohistochemical study of lymphocyte and macrophage infiltration in tumor tissue of 84 vulvar cancer patients with a long (over 2 years) and short (less than 2 years) remission was performed to determine a possible role of immunologic microenvironment of tumors in maintaining remission. Vulvar cancer patients with a short remission period were aged 46-85 years, mean age 67 years. 15.8% of them had stage I of the disease, 21% - stage II, 47.4% - stage III and 15.8% - stage IV. The average duration of remission in this group was 11 months. Patients with a long remission period were aged 27-71 years, mean age 48 years. 38.5% of them had stage I of the disease, 53.8% - stage II and 7.7% - stage III. The average duration of remission in this group was 8 years. Histological study showed squamous cell carcinoma in all patients. Stroma and parenchyma of tumor tissues demonstrated lymphocyte and macrophage infiltration of various degrees with the predominance of T-lymphocytes. CD8+ cells prevailed in tumor tissue of patients with a long remission period (over 2 years), while a higher level of CD4+ Т-lymphocytic infiltration was associated with a short remission (less than 2 years) and a poor prognosis. These differences allow prediction of the vulvar cancer course and its early or late recurrence