Acceptable values of the drainage hole parameters in the shunt glaucoma surgery were calculated by means of mathematical modeling of different conditions of eye hydrodynamics. The operation method was designed with provision for pressure gradient, rate of the aqueous humor outflow, and the values of intraocular pressure in early and late postoperative period. The balance of liquid in eye was calculated in mathematical model as ordinary differential equation in accordance with flow resistance of every section. The data received by using mathematical model has shown that allowable rate of aqueous humor outflow is gained with the hole diameter of 0,025 mm. This mathematical model should assist to the better understanding of physical processes describing the eye hydrodynamics, should benefit to the operation quality and should create the base to the clinical studies
The dramatic lowering of intraocular pressure (hypotony) is developing during glaucomatous surgery due to the formation of the new aqueous humor outflow. The calculations of the flow in the fluid balance parameters have shown, that for the normal intraocular pressure maintenance in the postoperative period the fluid flow out of the anterior chamber should not exceed 0,04 microliter in minute. The intensity of the aqueous humor outflow through the shunts with different parameters does not depend on the shunt length. The shunt with the inner hole radius 0,025 mm is the most safe as it provide the less outflow. The experimental comparative study of the static viscosity of the most widely used viscoelastics in ophthalmological surgery was carried out. It was stated that used in eye surgery viscoelastics on the basis of 1%, 2% and 3% sodium hyaluronate possess the viscosity, that differs in 10 and 100 times and has significant influence on the flow intensity out of the anterior chamber when the new outflow tracts are formed. The mathematically based choice of the most optimal relationship between the viscoelastics physical parameters and the inner hole size of the shunt type glaucoma drainage devices was established. Shunt with the inner hole radius 0,05 mm and simultaneous use of 2% and 3% sodium hyaluronate solution is the most safe for the maintenance of the eye tonus during the first 5 days after glaucoma surgery. The presented correlation allows to increase the safety of the surgical treatment of the patients with the refractory glaucoma
The article describes the visualization of the space of initial excitation area in sinoatrial node of the cat’s heart
Recently, much attention is paid to research the role of cell-cell interactions by gap junctions in the process of malignant transformation and mechanisms of antitumor resistance. Meanwhile, the greatest interest is astrocytic tumors. Depending on the degree of malignancy, astrocytomas are divided into: pilocytic astrocytoma (Grade I), subependymal giant cell astrocytoma (Grade I), pleomorphic xanthoastrocytoma (Grade II), diffuse astrocytoma (Grade II), anaplastic astrocytoma (Grade III), glioblastoma (Grade IV ) gliomatosis cerebri (Grade IV). Information of literature devoted to astrocytic tumors (gliomas) - the most common brain tumor in large part obtained in studies in cell cultures and different contradictions. Along with data on the reduction of glial tumors cells communicability through GJ, there is evidence of an opposite character - a functionally active GJ in gliomas and inhibition of tumor growth by reducing intercellular communicability by GJ. However, up to now there have been no studies of the effect and function of hemichannels in cancer cells, which would provide detailed information on: 1) the characteristic of presence and relative abundance of hemichannels in cancer cells; 2) evaluation of absorption / release of hemichannels mediated molecules in tumor cells than in non-tumor cells; 3) functional consequences of activation and blocking of hemichannels in tumor cells and 4) the prognostic value of the expression / activation of hemichannels in human malignancies
Comparative analysis of the informativity of ultrasonic
and radiographic examination of the lungs at the initial
diagnosis of inflammatory infiltrate and at case followup
of its involution during treatment was performed in
154 children with pneumonia. Higher informativity of
ultrasound compared with radiography was
determined. All children underwent ultrasound
monitoring of pneumonia since admission to the full
restoration of normal ultrasound image. Assessment
criteria of pneumonia involution were the size and
echostructure of an airless zone. Stationary ultrasound
was performed at least 3 times. Outpatient ultrasound
was repeated at least 2 times within 1 month, in some
cases children were observed up to 3 months with
monthly dualfold study
The aim of this work: a study of health - social and ethical aspects of health care workers in the framework of the prevention of a healthy lifestyle among youth. To study the level of students' knowledge about HIV prevention and detection of bad habits - drinking, smoking, drug addiction, a study author profiles. We
have used empirical, sociological and statistical methods
The article presents the results of the evaluation stress resistance among servicemen in the area of special risk on heart rhythm variability parameters
The article presents the evaluation of the lability of the visual analyzer among healthy individuals and patients with lesion after a stroke in the occipital cortex, temporal and parietal lobes
This article presents the results of regulation adaptive status when decreasing kidneys filtration capacity
Study was performed on 12 samples of astrocytic human brain tumors, which differ by the level of malignancy and histological indications. The study was conducted with the method of immunohistochemistry using a commercially available antibody anti-connexin-43 (Cx 43), a prior test of
which was carried out on myocardium tissue of rats (positive control). The study showed that with the increasing of malignant level of astrocytomas, there was marked the decreased level of connexin-43 expression of, which is apparently to be associated with the destruction of intercellular gap junctions in tumor tissue