Scientific Journal of KubSAU

Polythematic online scientific journal
of Kuban State Agrarian University
ISSN 1990-4665
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12514 kb

AUTOMATED SYSTEM-COGNITIVE ANALYSIS OF ANTIBIOTICS IN VETERINARY MEDICINE

abstract 1401806033 issue 140 pp. 163 – 212 29.06.2018 ru 26
Antibacterial chemotherapeutic drugs, which include antibiotics and synthetic antimicrobial agents, are widely used in veterinary medicine for the prevention and treatment of diseases caused by microorganisms. Antibacterial agents can be classified by type of action and chemical structure. It is also known that when several drugs are used in combination with each other, they interact within the body with each other, which can lead to strengthening or weakening of their action. For these reasons, it is of scientific and practical interest to develop a classification of antibiotics by their characteristics and principle of action (task 1), as well as by mutual compatibility (task 2). The article solves these problems using a new method of agglomerative cognitive clustering, implemented in automated system-cognitive analysis (ASK-analysis). This method of clustering has a number of advantages over the known traditional methods of clustering. These advantages allow us to obtain clustering results that are understandable to specialists and amenable to meaningful interpretation, which are well consistent with the experts ' assessments, their experience and intuitive expectations, which is often a problem for classical clustering methods. The article provides detailed numerical examples of solving two problems. The universal automated system called "Eidos", which is a tool of ASK-analysis, is in full open access on the author's website: http://lc.kubagro.ru/aidos/_Aidos-X.htm. Numerical examples of solving veterinary problems with the use of artificial intelligence technologies are placed as cloud Eidos-applications and are available to everyone
406 kb

RISK ANALYSIS AND FORECAST OF THE WORLD EPIZOOTIC SITUATION OF LUMPY SKIN DISEASE OF CATTLE FOR THE PERIOD UP TO 2030

abstract 1391805032 issue 139 pp. 83 – 98 31.05.2018 ru 26
The article represents the results of studying the spatial-dynamic factors and revealing the regularities of the global spread of Lumpy skin disease in cattle. The developed risk analysis and epizootological forecast provides the keeping up with a multi-year trend for the growth of epizootic tension in this disease for the period up to 2030. The highest probability of disease registration from 0.6 to 1.0 is predicted for the tropical agroecosystems of the African continent (enzootic zone) in 2018-2030. There is a real risk of disease in neighboring countries of Eurasia with the probability is less than 0.4. In the Russian Federation, outbreaks can occur in all federal districts of the country, but the highest probability of its occurrence is possible in agroecosystems of the subtropics of the North Caucasus and Southern Federal Districts of the country
2201 kb

AGGLOMERATIVE COGNITIVE CLUSTERING OF SYMPTOMS AND SYNDROMES IN VETERINARY MEDICINE

abstract 1391805033 issue 139 pp. 99 – 116 31.05.2018 ru 22
In the article, on a small numerical example, we consider the similarity and difference of symptoms and syndromes according to their diagnostic meaning, i.e. according to the information they contain about the belonging of conditionals of animals to different nosological images. This problem can be solved for veterinary with the use of a new method of agglomerative cognitive clustering, implemented in Automated System-Cognitive analysis (ASC-analysis). This method of clustering differs from the known traditional methods in: a) in this method, the parameters of the generalized image of the cluster are calculated not as averages from the original objects (symptoms) or their center of gravity, but are determined using the same basic cognitive operation of ASC-analysis, which is used to form generalized images of the classes based on examples of objects and which really correctly provides a generalization; b) the similarity criterion is not the Euclidean distance or its variants, but the integral criterion of non-metric nature: "the total amount of information", the application of which is theoretically correct and gives good results in unortonormated spaces, which are usually found in practice; c) cluster analysis is carried out not on the basis of initial variables, frequency matrices or matrix of similarity (differences), depending on the units of measurement on the axes (measurement scales), but in cognitive space, in which one unit of measurement is used for all axes: the amount of information, and therefore the results of clustering do not depend on the initial units of measurement of features of objects. All this allows us to get the results of clustering, understandable to specialists and amenable to meaningful interpretation, well-consistent with the experts ' assessments, their experience and intuitive expectations, which is often a problem for classical clustering methods
1070 kb

AGGLOMERATIVE COGNITIVE CLUSTERING OF NOSOLOGICAL IMAGES IN VETERINARY MEDICINE

abstract 1381804033 issue 138 pp. 122 – 139 30.04.2018 ru 29
The article deals with the similarity and difference of nosological images in veterinary medicine using a new method of agglomerative clustering implemented in Automated system-cognitive analysis (ASC-analysis) on a small numerical example. This method is called Agglomerative cognitive clustering. This method differs from the known traditional facts: a) parameters of a generalized image of the cluster are computed not as averages from the original objects (classes) or their center of gravity, and are defined using the same underlying cognitive operations of ASC-analysis, which is used for the formation of generalized images of the classes on the basis of examples of objects and which is really correct and provides a synthesis; b) as a criterion of similarity we do not use Euclidean distance or its variants, and the integral criterion of non-metric nature: "the total amount of information", the use of which is theoretically correct and gives good results in non-orthonormal spaces, which are usually found in practice; c) cluster analysis is not based on the original variables, matrices of frequency or a matrix of similarities (differences) dependent on the measurement units of the axes, and in the cognitive space in which all the axes (descriptive scales) use the same unit of measurement: the quantity of information, and therefore, the clustering results do not depend on the original units of measurement features. All this makes it possible to obtain clustering results that are understandable to specialists and can be interpreted in a meaningful way that is in line with experts' assessments, their experience and intuitive expectations, which is often a problem for classical clustering methods
314 kb

METHOD OF SELECTION OF QUAILS

abstract 1381804034 issue 138 pp. 140 – 148 30.04.2018 ru 93
The article is devoted to the method of selecting quails. Intensive development of re-fishing requires the development of breeding methods for selecting birds and to carry out early predictions of egg production. Targeted breeding selection is able to influence the mechanisms of correlation dependencies between individual parts of the animal's organism, significantly change even firmly established interrelations, and create new interactions more satisfying the needs of the individual. The research task consisted of establishing links between the parameters of the skeleton and the productive qualities of the layers. The studies were conducted on Texas white quails. We took into account the live weight of the bird, the length of the metatarsal and the third finger, as well as the small and large diameters of the metatarsal. Correlations were established between the length of the pelvic limbs and the live weight of young quails during growth. It is established that the growth of the skeleton ends with the age of onset of puberty. This provides a basis for predicting the live weight, depending on the length of the pelvic extremities. It is established that the live mass is directly related to the egg productivity of quails. Thus, by selecting the birds with the longest plus, it makes it possible for 25 weeks of productivity to increase the egg laying on the initial layer by 5,7 eggs and 6,2 eggs per average laying hen, respectively
331 kb

CORRECTION OF HOMEOSTASIS OF THE ORGANISM OF LARGE CATTLE AT THE NODULAR DERMATITIS

abstract 1381804035 issue 138 pp. 149 – 159 30.04.2018 ru 96
We have studied biochemical changes in the body of cattle, sick with nodular dermatitis in the initial stage of the clinical manifestation of the disease. It is proved that in case of disease in animals there is a significant increase in the level of creatinine up to 295.5 mg%. The excess of the norm by 82.1%. In treatment, this indicator was significantly reduced (189.2 mg%), but did not reach the upper limits of the norm (162.4 mg%). In the blood serum of patients, the carotene content was reduced to 0.09 mg%, which was restored to normal three days after the start of treatment (1.0 mg%). The glucose level at the beginning of the disease was 18% below normal and reached the lower limit of the norm 8 hours after the start of treatment. When studying the activity of CKK, it was found that the activity of the enzyme in animals before the introduction of a 5% solution of sodium hydrogencarbonate is 82% higher than the upper limit of the norm. After the treatment, this indicator returned to normal. The inorganic phosphorus index did not reach the physiological norm (2.5 mmol / l) before and after treatment, and remained 11.6% higher (2.9 mmol / l), which indicates a violation of mineral metabolism in sick animals. The level of reserve alkalinity began to recover after 8 hours of observation and reached a minimum limit of 48.91 vol. % CO2. During the entire period of the experimental studies, before and after the administration of the drug, there were no significant changes in the biochemical parameters of total protein, calcium, vitamin E and urea. The nature of the established changes varied within the limits of physiological norms. The use of a 5% solution of sodium hydrogen carbonate in nodular dermatitis increases the effectiveness of symptomatic treatment, reduces the likelihood of complications and stimulates the production of specific antibodies against viruses and bacteria. We have recommended intravenous injection of 5% sodium hydrogencarbonate solution to sick animals at the rate of 1 ml per 1 kg of live weight of the animal three times with an interval of 3 days
21210 kb

AUTOMATED SYSTEM-COGNITIVE ANALYSIS IN VETERINARY SCIENCE (ON THE EXAMPLE OF DIAGNOSTIC TESTS DEVELOPMENT)

abstract 1371803031 issue 137 pp. 143 – 196 30.03.2018 ru 35
The article considers the application of Eidos intellectual technologies for implementation of developed veterinary and medical diagnostics statistical tests without programming in the convenient form for the individual and mass testing, the analysis of the results and development of the individual and group recommendations. It is possible to merge several tests in one supertest
589 kb

MONITORING OF ANTIBIOTIC RESISTANCE OF ENTEROBACTERIA

abstract 1371803032 issue 137 pp. 197 – 206 30.03.2018 ru 25
Relative to the emergence and wide extension of an antibiotic resistance in infectious agents of animal infectious diseases, the particularly important assessment increases over change of sensitivity of various groups of microorganisms to anti-infective drugs. Results of studying antibiotic sensitivity of the enterobacteria isolated from an intestine of sick calves, and dynamics of its change within three years are presented in article. Results of the research demonstrate prevalence of resistance to the majority of anti-infective drugs (AID) among the Enterobacteriaceae isolates emitted from calfs. To chloramphenicol, neomycin and streptomycin from 100% of isolates E. coli, Proteus, Enterobacter, Morganella, Citrobacter were sensitivity. From AID of group of aminoglycosides gentamycin, from group of quinolones – enrofloxacin was the most effective. The good sensitivity to a polymyxin was shown to 80 % of isolates E. coli, Citrobacter spp., Klebsiella spp. It was established that 66,7 % of E. coli isolates, 57,1 % of Enterobacter spp., 75 % of Morganella, 60 % of Edwardsiella, 42,9 % of Citrobacter spp., allocated from sick calfs, has fastness to 7 AID. At the same time to other AID of a series the appreciable number of multiresistant strains shows weak sensitivity. The tendency of augmentation of number of antibiotic resistance isolates to AID which are widely applied in veterinary practice as time passed. High frequency of the combined resistance to traditionally used antibiotic drugs – to kanamycin (up to 80 %), to tetracycline (up to 85 %) and to chloramphenicol (up to 8 3%) testifies to need of obligatory test for sensitivity to AID before their use
156 kb

KINDS OF HELMINTHOCENOSIS, SPECIES COMPOSITION OF ASSOCIATIVE GROUPINGS IN POPULATIONS OF DIFFERENT BREEDS OF CHICKENS, IN THE BIOCENOSES OF PEASANT FARMS IN THE SUBURBS OF THE CITY OF KRASNODAR

abstract 1371803033 issue 137 pp. 207 – 219 30.03.2018 ru 39
This article is devoted to a comprehensive survey of parasitocenosis in 5 peasant farms content 1156 birds, 8 species of chickens, the minimum number in a separate farm was -26 birds, maximum -535. This is the first publication in which the material on helminthocenosis is presented as an integral part of parasitocenosis of individual bird species (intensity of infestation, extensiveness of infestation, associative groupings). The rest of the material on mites, puffers, and bloodsuckers, coccidia, histomonads, microfauna, will be presented in the next publications
192 kb

DISPERSAL OF COLIBACILLOSIS IN PIGS AND THE WAY OF ITS SPECIFIC PROPHYLAXIS

abstract 1371803036 issue 137 pp. 220 – 229 30.03.2018 ru 44
One of the most widespread infections affecting newborn pigs is colibacillosis. The set of factors contributes to the development of this disease: non-compliance with elementary veterinary health regulations of conducting pig-breeding, an error in technologies of contents and feeding, stressful situations, and as a result, emergence of the specific factors contributing to illness emergence (dysbacterioses, activation of conditionally pathogenic microflora). In addition, not always specific prophylaxis of colibacillosis is in due time and successfully carried out that is generally bound to disharmony of antigenic composition vaccine drug and originator of the pathogenic potential. In this connection, use of new agents and ways of improvement of prophylaxis of colibacillosis for pigs is represented a current problem in veterinary medicine. The purpose of this work was studying diffusion of colibacillosis among bacterial infections of pigs and establishment preventive efficiency of colibacillosis anatoxin at vaccination the pregnant pigs. Dispersal of colibacillosis was studied in a complex with use the epizootological, anamnestic, clinical, pathologicoanatomic, bacteriological methods of research and also on basis materials the veterinary reports of economy. Allocation of microorganisms was carried out with use differential and diagnostic, selective mediums, identification − with use of traditional methods of bacteriological diagnostics, on the basis cultural, the tinktorial and biochemical properties. Researches showed what colibacillosis at pigs is registered in 37,5-51,4% of cases and wins first place among infections of pigs of a bacterial etiology. When studying efficiency prophylaxis of colibacillosis with bacterination use the pregnant pigs anatoxin containing three types inactivated by formalin exotoxins of the Escherichia coli, have established decrease in indicators of incidence and lethality also high safety of pigs (96%) concerning Escherichia coli
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