Scientific Journal of KubSAU

Polythematic online scientific journal
of Kuban State Agrarian University
ISSN 1990-4665
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Name

Gorpinchenko Evgeny Anatolyevich

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associated professor

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Kuban State Agrarian University
   

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Articles count: 7

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145 kb

DETERMINATION OF ACUTE TOXICITY OF ROKSATSIN

abstract 1211607124 issue 121 pp. 1975 – 1984 30.09.2016 ru 404
In this article, the authors have defined the acute toxicity of Roksatsin preparation, which represents a 20 % aqueous solution of polyhexamethylene guanidinehydrochloride (PHMG). The acute toxicity of Roksatsin in the first series of experiments was studied on white mice upon intragastric administration. In the second series of the experiments, Roksatsin was administered subcutaneously to white rats and in the third series of experiments the preparation was administered intracisternally to cows. The results of the first series of experiments showed that Roksatsin by the internal method of appointment is slightly toxic to white mice. In this experiment not been a single case of acute intoxication and death of animals. Experiments to determine the acute toxicity of the preparation for white rats were performed in triplicate. In the first series of experiment, the LD50 was 4.8 ml/kg. It is found, that the calculated coefficients LD50 for other two series were close to the first one: the second - 4.2 ml/kg and the third - 4.5 ml/kg. Therefore, the authors found that the Roksatsin preparation upon subcutaneously administration according GOST 12.1.007-76 is a low-toxic compound (4th class of danger). As a result of the third series of the experiments, it was found that the intracisternally administration of Roksatsin preparation to cows in a dose of 5 ml is not toxic to the animal organism. Intracisternal administration of Roksatsin does not have a significant impact on the morphological and biochemical indices of blood. On this basis, Roksatsin preparation with different routes of administration is low-toxic and it can be recommended for clinical researches
183 kb

EFFICIENCY OF ROKSATSIN IN AEROSOL DISINFECTION OF THE LIVESTOCK BUILDINGS

abstract 1211607125 issue 121 pp. 1985 – 1994 30.09.2016 ru 384
The authors briefly describe the properties of polyhexamethyleneguanidine hydrochloride (PHMG), which refers to a broad-spectrum biocide and has antimicrobial activity against Gram-negative and Gram-positive bacteria, viruses and fungi. PHMG has a deodorizing effect, gives the treated surfaces long bactericidal effect, which can be stored depending on the surface and other external factors from 3 days to 8 months. The authors have presented data about the level of bacterial and fungal contamination of air in the dispensary before and after aerosol treatment of Roksatsin. Bacterial contamination of air dispensary determined via the sedimentation method (Koch Method), which is settling microflora (in air), under gravity, on the surface of a growth medium. For the determination of total bacteria and fungi in 1m3 of air the authors make calculations of total aerobic microbial count (TAMC) according to the formula that was proposed by V.L. Omelyanskii. Bacterial contamination of air was evaluated before disinfection. Accounting quality of aerosol disinfection performed by sedimentation microflora on Petri Dishes through 30, 60 and 120 minutes of exposition. In the analysis of the data the authors defined that Roksatsin as a disinfectant has a negative effect on pathogens, namely significantly reduced the content of pathogenic and conditionally pathogenic bacteria and fungi in the air, so it can be used for preventive and compelled aerosol disinfection of air in the livestock buildings
186 kb

FACTORS CONTRIBUTING TO THE EMERGENCE OF FUNCTIONAL DISORDERS OF BIRTH-GENITAL APPARATUS AT COWS

abstract 1211607113 issue 121 pp. 1818 – 1827 30.09.2016 ru 246
ЖИВОТНОВОДСТВО, КРУПНЫЙ РОГАТЫЙ СКОТ, ДИСФУНКЦИЯ ЯИЧНИКОВ, ЭНДОМЕТРИТ, БЕСПЛОДИЕ, СУБИНВОЛЮЦИЯ МАТКИ, ПОЛОВОЙ ЦИКЛ, ПЕРСИСТИРУЮЩЕЕ ЖЕЛТОЕ ТЕЛО, КИСТА ЯИЧНИКОВ, ГОРМОНЫ
117 kb

INDUCTION AND SYNCHRONIZATION OF REPRODUCTIVE FUNCTION OF DAIRY COWS IN INDUSTRIAL COMPLEXES

abstract 0981404015 issue 98 pp. 211 – 217 30.04.2014 ru 1512
Based on analysis of the etiopathogenesis of ovarian follicular cysts in cows and heifers we have developed a comprehensive method of treatment and prevention of them. Potassium iodide normalizes metabolism and has specific effects on the genitals, thyroid and pituitary glands, restores their function. Chlormadinone inhibits the secretion of pituitary gonadotropins depending on the dose of the drug, and estrofan promotes growth of ovarian follicles and the manifestation of hunting and estrus in cows
139 kb

THE CAUSAL AND INVESTIGATORY FACTORS OF FUNCTIONAL DISORDERS OF UTERUS AND OVARIES AT COWS ON INDUSTRIAL FARMS

abstract 1211607112 issue 121 pp. 1809 – 1817 30.09.2016 ru 471
According to the title, the article describes the causes and contributing factors of functional disorders of the uterus and ovaries at cows. The authors specified the percentage incidence of these animals’ pathologies in some farms of Krasnodar Region, especially in industrial complexes. Studies have shown that acute postpartum endometritis has a definite influence on the functional disorders of the ovaries at cows. Authors have found that the cows via 2-4 months after calving with ovarian hypofunction in early postnatal period have had purulent-catarrhal endometritis in 87.9%, fibrinous - in 12% of cases. At cows which have had persistent corpus luteum in 54.6% of cases was registered purulent-catarrhal endometritis, in 27.6% - fibrinous, in 17.8% - necrotizing metritis. At cows with ovarian cysts fibrinous endometritis was observed in 63.2% of cases, necrotizing metritis - in 36.7%. Thus, the more severe form of uterine inflammation was observed in cows, the more severe form of ovarian functional disorders observed in them. The authors found that any factors which negatively acting on the central nervous system or hormone levels, directly or indirectly, sharply reduce the reproductive function of animals
109 kb

THE METHOD OF TREATMENT AND PREVENTION OF FOLLICULAR OVARIAN CYSTS IN COWS AND HEIFERS IN BEEF CATTLE

abstract 0981404005 issue 98 pp. 79 – 85 30.04.2014 ru 1827
The article presents positive results of application of integrated ways (methods) of induction and synchronization of the sexual cycle in cows for wide practical application in accelerated (extended) reproduction of the herd cattle
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