Scientific Journal of KubSAU

One of the most widespread infections affecting newborn pigs is colibacillosis. The set of factors contributes to the development of this disease: non-compliance with elementary veterinary health regulations of conducting pig-breeding, an error in technologies of contents and feeding, stressful situations, and as a result, emergence of the specific factors contributing to illness emergence (dysbacterioses, activation of conditionally pathogenic microflora). In addition, not always specific prophylaxis of colibacillosis is in due time and successfully carried out that is generally bound to disharmony of antigenic composition vaccine drug and originator of the pathogenic potential. In this connection, use of new agents and ways of improvement of prophylaxis of colibacillosis for pigs is represented a current problem in veterinary medicine. The purpose of this work was studying diffusion of colibacillosis among bacterial infections of pigs and establishment preventive efficiency of colibacillosis anatoxin at vaccination the pregnant pigs. Dispersal of colibacillosis was studied in a complex with use the epizootological, anamnestic, clinical, pathologicoanatomic, bacteriological methods of research and also on basis materials the veterinary reports of economy. Allocation of microorganisms was carried out with use differential and diagnostic, selective mediums, identification − with use of traditional methods of bacteriological diagnostics, on the basis cultural, the tinktorial and biochemical properties. Researches showed what colibacillosis at pigs is registered in 37,5-51,4% of cases and wins first place among infections of pigs of a bacterial etiology. When studying efficiency prophylaxis of colibacillosis with bacterination use the pregnant pigs anatoxin containing three types inactivated by formalin exotoxins of the Escherichia coli, have established decrease in indicators of incidence and lethality also high safety of pigs (96%) concerning Escherichia coli

Smallpox of turkey is a viral, slowly extending disease. It pathogenetically proceeds in a dermatotropic way, skin lesions are characterized primarily by two signs or focal necrotic focus centers or diphtheritic inflammation of mucous membranes, often of the upper respiratory tract. Etiological factor in smallpox are dermatotropic epitheliogenic viruses, the family of Avipoxvirus of Poxviridae. The purpose of this work was studying the features of clinic and the pathomorphological changes at smallpox at turkeys in the context of diagnostics methods and also generalization of treatment-and-prophylactic actions at this pathology. The diseased bird is the main source of infection. In addition, the smallpox virus particles can be spread by people providing care for the birds, indoor air, food, bedding material, excrement. Diagnosis of smallpox takes into account the symptoms; if an autopsy was performed, the result of a pathological pattern as well. Additionally, we can conduct a research of histological sections. Confirmation of diagnosis can be performed by a virological study and the blood serum. In accordance with the pathogenesis of smallpox, there is a classic skin form and diphtheritic. There may be a combination of the above manifestations of smallpox, therefore we can record the mixed form, in some cases, it may be atypical. Pathoanatomical changes come down to defeat a respiratory system of bodies, the upper airways, at the complicated forms there may be noted lesions in the internal organs. Laboratory methods include identification of the virus in the pathological material, as well as additional histological and virological studies using chicken embryos and bioassays. Treatment is difficult and not always effective. The main preventive measure against smallpox in turkey is vaccination, basic applied biologics are: Avivac-pox" strain "K", "Ospovat, Vectorman FP-MG". Prevention of smallpox includes the implementation of general veterinary and sanitary rules in conjunction with the mandatory special prevention. When planning measures to prevent the spread of smallpox, conditions are created to eliminate pathways of transmission of the pathogen – disinfection, disinsection and deratization, as well as vaccination of all susceptible livestock

One of the reasons extensions acute intestinal diseases in newborn calves and piglets is absence at them of formed immune system and colonization resistance. For this reason, their intestine often occupies relative pathogenic microorganisms, which in the subsequent cause diarrheal diseases. The characteristic feature of the last time is the fact that these diseases have the associated disposition and composition of association can be the most various but not only biological objects (for calves and piglets), and also territorial borders. The goal of this work was in comparative study of the structure microorganisms, which were isolated from newborn calves and piglets at acute intestinal diseases in Krasnodar territory and the establishment of the dominant species. During the bacteriologic examination of pathological material was detach and finger 1299 isolate calves and 476 from piglets which was found to belonged to 6 families: Enterobacteriaceae, Streptococcaceae, Enterococcaceae, Pseudomonadaceae, Alcaligenaceae, Alteromonadaceae. Studies have shown that dominant logic value in nosological profile of the allocated bacteria belongs to enterobacterium, enterococcus, streptococcus, the share of which in the general pool of isolates has made 70,1%, 15,9% and 11,1%, respectively. At the same time among the enterobacterium detached as from calves, and pigs, the prevailing species was E. coli (55,6%), streptococcus – S. bovis (24,9%), enterococcus – E. faecium and E. faecalis (88,3%). Meanwhile, along with the general character of frequency separation of certain types of bacteria, also their specific preference is set. That why from calves there were more often selected enterobacter, citrobacter, kluyvera, E. faecalis, S. cricetus, S. mitior, S. parauberis and P. aeruginosa. Whereas from pigs more often were allocated protei, providencia, shigella, E. mundtii, E. casseliflavus, S. acidominimus, S. oralis, S. pneumoniae, S. vestibularis и Alcaligenes fecalis than from pigs

The article presents data on the prevalence of colibacillosis of pigs in farms of the Krasnodar region in the period 2010-2016. Colibacillosis is widespread in pig farms of the Krasnodar region. In different years, it was recorded at 32.6 - 55.6% of bacterial infectious diseases of pigs. And only in 2013-2014, in farms of the region colibacillosis was not registered. Among the bacterial pathology, colibacillosis in pigs in the farms of the Krasnodar region is in the first place after staphyloccocus (3 - 15 %), streptoccocus (2-13,7 %), and diseases caused by conditionally pathogenic microflora (17,9-20 %). In the Krasnodar region, we annually allocate different serotypes of E. Coli that vary depending on areas and farms, however, regularly in pigs in the Krasnodar region there are the following serotypes: A8, О20, О119, О26, О86 in Bryukhovetskiy, Dinskoy, Kalininskiy, Korenovskiy, Kurganinskiy, Kushchevskaiy, Labinskiy regions of the Krasnodar territory. According to the reports of outbreaks, colibacillosis in pigs for several years were recorded in the Central, Korenovskiy, Kushchevskaya, Labinskiy, Primorsko-Akhtarskiy, Seversky, Slavyanskiy, Tbilisskiy, Timashevskiy, Ust-Labinskiy districts of the Krasnodar region and in the city of Krasnodar. After 2013-2014, after the total absence of the disease in the region, there were reported outbreaks in 2015 in some farms in the Timashevskiy district, and in 2016 – in Kurganinskiy