Name
Makarov Yury Anatolyevich
Scholastic degree
•
Academic rank
professor
Honorary rank
—
Organization, job position
Kuban State Agrarian University
Web site url
—
Articles count: 3
The article presents results of researches of authors on prevalence of a canicola fever in populations of cattle and wild rodents in the Amur region. The research objective consisted in studying of etiological structure of a canicola fever of cattle and establishment of the dominating canicola fever originator serotypes at the rodents living in the Amur region. Results of researches showed that in etiological structure of a canicola fever of cattle in the Amur region the admixed serogroups and a serogroup of Sejroe dominate. The natural reservoir of a canicola fever in the Amur region are populations of gophers, chipmunks, muskrats and voles. The highest percent of the infected individuals is taped in population of gophers (57,1 %). Level of contamination of animals in populations of muskrats and chipmunks made 20 and 17,6 % respectively. Contamination the canicola fever originator in populations of voles was at the level of 8-9 %
Results of studying of the immune response of young
growth of cattle to vaccination against a canicola fever
are presented in article. Dependence of duration of
circulation of antibodies in a blood of the vaccinated
young growth of cattle from degree of intensity of an
immune response on introduction of the vaccine is
revealed. Studying of dynamics of antiserum capacities
at cow calves of two-month age after immunization
taped the weak immune response on introduction of a
vaccine. It is expressed both in total absence of
antibodies, or available antibodies in minute quantity
to canicola fever of one of the serogroups which are a
part of a vaccine. Use of immunomodulatory
preparations for rising of efficiency of immunization
of cow calves against a canicola fever is offered. It is
established that application of "Ribotan" at vaccination
of two-month calves against a canicola fever increases
efficiency of immunization for 55,6 %
Relative to the emergence and wide extension of an antibiotic resistance in infectious agents of animal infectious diseases, the particularly important assessment increases over change of sensitivity of various groups of microorganisms to anti-infective drugs. Results of studying antibiotic sensitivity of the enterobacteria isolated from an intestine of sick calves, and dynamics of its change within three years are presented in article. Results of the research demonstrate prevalence of resistance to the majority of anti-infective drugs (AID) among the Enterobacteriaceae isolates emitted from calfs. To chloramphenicol, neomycin and streptomycin from 100% of isolates E. coli, Proteus, Enterobacter, Morganella, Citrobacter were sensitivity. From AID of group of aminoglycosides gentamycin, from group of quinolones – enrofloxacin was the most effective. The good sensitivity to a polymyxin was shown to 80 % of isolates E. coli, Citrobacter spp., Klebsiella spp. It was established that 66,7 % of E. coli isolates, 57,1 % of Enterobacter spp., 75 % of Morganella, 60 % of Edwardsiella, 42,9 % of Citrobacter spp., allocated from sick calfs, has fastness to 7 AID. At the same time to other AID of a series the appreciable number of multiresistant strains shows weak sensitivity. The tendency of augmentation of number of antibiotic resistance isolates to AID which are widely applied in veterinary practice as time passed. High frequency of the combined resistance to traditionally used antibiotic drugs – to kanamycin (up to 80 %), to tetracycline (up to 85 %) and to chloramphenicol (up to 8 3%) testifies to need of obligatory test for sensitivity to AID before their use