Name
Sereda Alexey Dmitrievich
Scholastic degree
•
Academic rank
professor
Honorary rank
—
Organization, job position
State Research Institution National Research Institute of Experimental Veterinary
Web site url
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Articles count: 3
Some optimal conditions to fix virus-specific anticellular effectors of immunity at African swine fever (ASF) were determined. Injection of an attenuated strain FK-135 at high doses enables registration of antibodies active in antibody-dependent cellular toxicity (ADCT) and primary cytotoxic T-lymphocytes (CTL) on days 3 and 6, respectively. After infection of pigs with a virulent strain F-32 not any immunity anticellular effectors were found
Gamma irradiation-inactivated cultural preparations (-IP) of African swine fever (ASF) non-haemadsorbing strains acquire a potential for haemadsorption induction in porcine bone marrow culture (PBMC). We have obtained some experimental data indicating that a modification of haemadsorption inhibition assay (HIA) which is an assay aimed at “removal” of γ -IP-induced haemadsorption may be used in research works to determine serospecificity rates of ASF virus non-haemadsorbing isolates
The review presents some data on structural and non-structural, regulatory proteins and enzymes of African swine fever (ASF) virus. The variety of the virus biological characteristics is substantially caused by proteins belonging to multigenic families. It is suggested, that the protection development at ASF is provided not only by the membrane proteins, but also by the regulatory ones