Scientific Journal of KubSAU

The article provides a review of domestic patent information on the effectiveness of using modern probiotic feed additives in pig farming practice. The inclusion of probiotic feed additives in the diets of pigs is aimed at excluding pathogenic and opportunistic microflora from the intestinal microbiocenosis, increasing the productive action of feed and intensifying metabolic and immune processes in the organism. The introduction of probiotic feed additives into the diet of pregnant sow and suckling pigs, as well as weaned piglets, allows achieving high indicators for the safety and productivity of young animals, which is very important for the cost-effective development of production. The ability of probiotic feed additives to normalize the microflora of the gastrointestinal tract of newborn piglets provides increased resistance to mass gastrointestinal diseases, as well as increasing the safety and viability of piglets. Thus, probiotic feed additives are an important component of the modern diet of farm animals at all stages of their development. At the same time, the most popular and effective for modern pig farming are multicomponent probiotic feed additives that contain a complex of probiotic cultures with different biological effects on the organism, sorbents that often act as prebiotics, enzyme preparations and other biologically active substances that provide a positive multifunctional effect on the organism of farm animals

The article presents the results of scientific and industrial experience in identifying the effect of feed additives on the productivity and biochemical parameters of bull calves’ blood in fattening. The calves of Holstein-Friesian breed at the age of 30 days were selected as objects of research. In the diet of the bull calves of the experimental groups, we used feed additives in the main diet: probiotic feed additive “Cellobacterin+”, feed vitamin-mineral concentrate “Tetra+”, complex feed concentrate. We found that the most active weight gain is observed in the group of calves that received complex feed concentrate. In all experimental groups of bull calves, we observed a decrease in the activity of hepato-indicator enzymes and a thymol sample. Based on the data obtained, it can be concluded that the use of the complex feed concentrate containing biologically active substances and the additive “Cellobacterin+” (in comparison with the control and other experimental groups) leads to maximizing the increase in the average mass of bull calves, which is associated with the synergistic effect of biologically active substances and living microorganisms Enterococcus faecium 1 - 35. The same tendency is observed with respect to the activity of hepato-indicator enzymes - AST and ALT, which, compared with the control group, decreases by 35.6% and 28.2%, respectively

Providing the population with basic food products, sources of proteins, fats, carbohydrates, vitamins and other essential nutrients is one of the main issues of ensuring the security of the country, while the requirement for food safety is paramount. Production of feed additives (concentrates), which improve feed conversion, while being natural and safe for animal health, acquires the greatest importance in the conditions of intensification of agriculture and increasing the competitiveness of livestock farms. Probiotic microflora, which, in competition with pathogenic, displaces the latter from the gastrointestinal tract, can be considered as one of the effective methods of controlling undesirable microflora in the digestive tract. In world science, research is actively conducted in the direction of searching for effective probiotic cultures. A promising way to increase the effectiveness of the use of probiotic feed additives is their addition to prebiotics, for example, including vitamins (antioxidants) and mineral substances (selenium). The purpose of this work was to determine the optimal ratio of biologically active substances contained in the feed vitamin-mineral concentrate, and probiotic microflora contained in the feed probiotic additive Bacell-M, for the development of complex feed concentrate. Using the Harrington's desirability function, the optimum ratio of biologically active substances and probiotic microflora in the recipe of the complex feed concentrate is determined, ensuring the maximum reduction in the serum levels of alanine aminotransferase in the blood serum of experimental animals, which characterizes the normalization of barrier organs

Providing the population with basic foodstuffs, sources of proteins, fats, carbohydrates, vitamins and other essential nutrients is one of the main issues of ensuring the security of the country, while the requirement for food safety is paramount. Production of feed additives (concentrates), which improve feed conversion, while being natural and safe for animal health, acquires the greatest importance in the conditions of intensification of agriculture and increasing the competitiveness of livestock farms. Probiotic microflora, which, in competition with pathogenic, displaces the latter from the gastrointestinal tract, can be considered as one of the effective methods of controlling undesirable microflora in the digestive tract. In world science, research is actively conducted in the direction of searching for effective probiotic cultures. A promising way to increase the effectiveness of the use of probiotic feed additives is their addition to prebiotics, for example, including vitamins (antioxidants) and mineral substances (selenium). The purpose of this work was to determine the optimal ratio of biologically active substances contained in the feed vitamin-mineral concentrate, and probiotic microflora contained in the feed probiotic additive Bacell-M, for the development of complex feed concentrate. Using the Harrington's desirability function, the optimum ratio of biologically active substances and probiotic microflora in the recipe of the complex feed concentrate is determined, ensuring the maximum reduction in the serum levels of alanine aminotransferase in the blood serum of experimental animals, which characterizes the normalization of barrier organs

The article provides an overview of domestic and foreign patent information on existing recipes and methods for producing complex feed additives containing probiotic microflora for cattle. Introduction of probiotic cultures of microorganisms to feed additives, along with biologically active substances, allows us to influence the processes of microbiocenosis of the intestines of animals, and, therefore, digestibility and digestibility of feed, which, in turn, leads to an increase in animal productivity. In addition, probiotic cultures contribute to the biodegradation of mycotoxins, which helps prevent mycotoxicity of animals. The most popular in modern livestock breeding are complex feed additives with broad-spectrum probiotic preparations, performing various biological functions

The article shows the historically developed situation and the actual state of the production practice in chronic mycotoxicosis of a bird. The main feed problems in poultry farming are shown through the prism of a review of market proposals for feed concentrates. An overview of preventive and compensating agents on the market, as well as a brief description of feed concentrates based on beta-carotene for fighting mycotoxicosis. It is shown that the vitamin-mineral fodder concentrate "Tetra +" is an alternative to the existing feed concentrates on the market, the effectiveness of which has been confirmed in experiments on laboratory animals and in poultry feeding. Based on the analysis, a conclusion was made about the relevance of studies to identify the effectiveness of vitamin-mineral concentrate "Tetra +" in livestock

The article describes the efficiency of a feed additive called "Tetra+" during chronic mycotoxicoses of pigs. The purpose of carrying out series of experiments on sows was to determine the therapeutic and prophylactic effectiveness of innovative feed additive "Tetra+" during combined chronic mycotoxicosis in pigs and to study the influence of feed additive on the growth, weight, preservation and overall resistance of sows. The results of the experiments revealed that a feed additive "Tetra+" has had a positive impact on large-fruited of pigs; it can also be concluded that the feed additive "Tetra+" has a positive effect on the metabolism of proteins, carbohydrates and has antitoxic properties

The results of the work experience carried out in the poultry breeding farm of Limited Liability Company «Incubator-poultry plant Pervomaiskaja» on the effect of the multifunctional feed additive «Tetra+» on productivity of males and laying hens in the production of broiler chickens. It is found that males experimental group receiving the feed additive in the diet «Tetra+» have better blood serum biochemical indices in comparison with the control group cockerels. This indicates that the feed additive «Tetra+» shows the properties to improve liver function and decreased intoxication of male manufacturers. It was revealed, that in the experimental group increased divorce figures, while the control group of males producing hatchability is reduced, and the end of observation of this indicator of the trend towards recovery is not evident. It recorded the highest percentage yield of hatching eggs from hens of the experimental group, while the control group showed a tendency to reduce this figure. Thus it may be noted that the use of a multifunctional feed additive "Tetra +" when feeding cocks and hens can improve productivity, reduce bird deaths and to strengthen the protective function of the body of birds

The article gives an overview of the current developments of scientists of the Russian Federation in the field of production of feed concentrates and premixes for cattle. A critical analysis of feed concentrates and premixes of preventive and compensatory action for the control of mycotoxicoses was carried out, and their brief characteristics were given. The characteristic of biologically active substances and fillers, declared in the recipes of feed concentrates and premixes, is given. It is shown that the alternative to existing feed concentrates and premixes on the market is vitamin-mineral fodder concentrate "Tetra +", developed by the authors. Based on the analysis, a conclusion was made about the relevance of studies to identify the effectiveness of vitamin-mineral fodder concentrate "Tetra +" in livestock