Scientific Journal of KubSAU

Polythematic online scientific journal
of Kuban State Agrarian University
ISSN 1990-4665
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Name

Kononenko Vladimir Ivanovich

Scholastic degree


Academic rank

associated professor

Honorary rank

Organization, job position

Rostov state medical university
   

Web site url

Email

rnioi@list.ru


Articles count: 1

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THE ROLE OF THE TRANSCRIPTION AND ANGIOGENESIS FACTORS IN THE PATHOGENESIS OF PURULENT POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH ORAL MUCOSA CANCER

abstract 1281704023 issue 128 pp. 330 – 341 28.04.2017 ru 180
While studying the content of hypoxia-inducible factor 1-alpha and vascular endothelial growth factor in the tumor tissue, oral fluid and peripheral blood of 141 patients with oral mucosa cancer T1-3N0-2M0, it was shown that the development of purulent inflammatory postoperative complications in patients with oral mucosa cancer is associated with an increased expression of HIF-1α in the tissue and its translocation from the cytoplasm to the nucleus, activation of the neoangiogenesis processes. It is informative to determine HIF-1α factor in the blood serum, which, for further development, can be used as a non-invasive diagnostic marker to predict the postoperative course in this category of patients
.