Scientific Journal of KubSAU

Polythematic online scientific journal
of Kuban State Agrarian University
ISSN 1990-4665
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Name

Semenenko Marina Petrovna

Scholastic degree


Academic rank

Honorary rank

Organization, job position

GNU Krasnodar NIVI
   

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Email

кrasnodarnivi @ mail.ru


Articles count: 8

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161 kb

BIOLOGICAL FUNCTIONS OF CAROTENOIDS AT CATTLE REPRODUCTION

abstract 1291705080 issue 129 pp. 1124 – 1136 31.05.2017 ru 87
Carotenoid preparations are quite widely used in a health care, but in the veterinary and animal husbandry, their use is limited. In terms of livestock farms of the Krasnodar region and the Rostov region at the biochemical monitoring studies of the cattle blood the lack of carotene in the serum is revealed from 45 to 100 % of the samples. To study the biological function of carotenoid we used preparations, which are the oily solutions for injections: β-carotene (manufactured by FS 42-3867, which is produced from the biomass culture of the fungus Blakeslea trispora) and lycopene, emitted from plants. The cows in the test groups during the dry period and within two weeks after birth got carotenoid preparation subcutaneously at a dose of 10 ml per animal with an interval of 7 days. As a result, it was found out that the application of carotenoids has the most favorable conditions for the flow of labor and the postnatal period, which are manifested in the decrease in obstetric and gynecological diseases in cows and reduce the period of infertility. In the experimental groups the levels of vitamin A and carotene1,3 times higher (1,26 ± 0,14 μmol/L vs. 0,97 ± 0,09 μmol/L ) 1,8 times (0,34 ± 0 03 mg /% vs. 0.61 ± 0.11 mg /%) respectively in comparison with the parameters of the intact animals at a high level of confidence (P < 0,05). Phagocytic number and percentage of digestion of neutrophils increased by 8,5 %, the difference in the number of B-cells reached 9,1%, T-cells – 6,7%. In a humoral immunity found a significant increase in Ig A. After comparison of the level of lysozyme activity of blood serum was observed its reduction in all animals immediately after birth, but in the experimental groups this process was less pronounced. The use of carotene preparations helps to reduce the concentration of lipid peroxidation products in the body of cows (diene conjugates - by 16,6 %, ketodienes - by 35,7 %, malondialdehyde – by 11,3 %), which creates favorable conditions for the flow of the metabolic processes associated with ensuring the normal childbirth and post-partum involution of the genitals. In the group of cows, receiving the carotenoid lycopene, the dyspepsia morbidity of the newborn calves compared to a control decreased by 26,7 %, bronchopneumonia - by 13,3 %
145 kb

CLINICAL PHARMACOLOGY OF A NEW COMPLEX HEPATOPROTECTIVE PREPARATION

abstract 1191605076 issue 119 pp. 1077 – 1088 31.05.2016 ru 148
This article presents the results of the studies of the influence of a new complex hepatoprotective preparation on the basic system of the body, the mechanism of occurrence and manifestation of its biological effects, the dependence of this action from the components that are parts of the preparation, the dose, as well as the regularity of manifestation of possible side effects. The effect of the different doses of the preparation (1% and 2%) on the average daily weight gain and morphological and biochemical indices of the birds’ blood was studied. The conducted research determined a stimulatory influence of the preparation on the growth, development and safety of broiler chickens. The new hepatoprotector exhibits the properties aimed on revitalizing the erythro- and hematopoiesis and magnification of the cellular immunity against the exogenous influence. The use of the preparation helps to improve liver function and reduce the toxic load on hepatocytes, which manifests an increase in a number of metabolic parameters, such as total protein, glucose, calcium, phosphorus. We have noted an expressed hepatoprotective effect on the enzyme activity of AST and the remission of the cytolytic syndrome of the experimental chickens. Thereby it was found out that the complex hepatoprotective preparation has a pronounced pharmacological activity, providing a significant impact on the energy of the broiler chickens’ growth and their safety, morphological and biochemical indices of the blood and metabolic processes in the body of the bird
122 kb

COMPLEX THERAPY AT OLIGOTROPHIES OF CALVES

abstract 0701106043 issue 70 pp. 608 – 617 30.06.2011 ru 1325
In the article, the effects of approbation of complex therapy are resulted at oligotrophy of calves with use of the preparation of protein hydrolysis and Dipromo-nium - M. The antihypotrophic action of preparations and efficiency of the scheme for augmentation of additional weights of calves and optimization of bio-chemical profile of blood are established
129 kb

CORRECTION OF THE SEASONAL ANEMIC STATE OF CALVES WITH THE USE OF COM-PLEX ALUMOSILICATE PREPARATION

abstract 0681104038 issue 68 pp. 419 – 428 28.04.2011 ru 1303
The influence of the complex alumosilicate prepara-tion of Silimix on productivity, rates of red blood cells and certain microcells in blood serum against nutri-tional anemia of calves is studied. The increase in additional weights of calves and antianemic effect of the preparation is established
211 kb

EXPERIENCE OF USING NATURAL MINERAL COMPOUNDS FOR METABOLIC DISORDERS IN CATTLE

abstract 1241610069 issue 124 pp. 1065 – 1084 30.12.2016 ru 147
In this study we show the results of the use of natural mineral compounds in metabolic disorders in cattle-breeding complexes of industrial type. According to official data for 2013-2015, based on the biochemical analysis of blood of cattle, that was held in some farms of Samara region, significant metabolic disorders were determined due to decrease in total protein level on 31,5% in average, decrease in alkali reserve – on 26,9% of samples, decrease in calcium concentration – on 40,7%, decrease of the phosphorus – on 8,1%, decrease in carotene – on 81,7% and glucose – on 84,3% of studies. Clinical examination of herd revealed a high level of animals with obvious signs of mineral metabolism disorders (osteodystrophy and rickets of alimentary origin) and comorbidity (nutritional anemia, gastroenteritis, pneumonia, disturbance of protein, carbohydrate and vitamin metabolism, and others). The use of complex natural compounds improves the efficiency of the traditional complex of treatment and prophylaxis, causing an increase in the total concentration of calcium in the blood serum on 10-55%, increase in calcium-phosphorus ratio till 1,27-2,3, increase in annual growth rate of young animals’ body weight on 8,2-44,8%, increase in milk production on 5,9-16,3%. Preparations have an antianemic action, normalize indicators of micronutrient metabolism of proteins and carbohydrates, enhance non-specific resistance factors and prevent the development of non-contagious internal pathology
144 kb

PHARMACODYNAMIC EFFECTS OF APPLICATION OF POLISILAR PREPARATION IN PIG PRODUCTION

abstract 1061502043 issue 106 pp. 688 – 699 28.02.2015 ru 365
An accelerated growth of farm animals in order to obtain maximum productivity is possible due to introduction stimulating additives and preparations based on them into the rations. One of such tools is Polisilar - complex preparation, which includes components that have a positive impact on various aspects of the animal metabolism in the conditions of physiological disorders. At the same time components of the preparation due to its high bioavailability exhibit a potentiating effect in the body that allows getting a more pronounced effect on its use. Studies were conducted on pigs 3-3.5 months age and showed that the Polisilar preparation has a positive effect on the clinical and physiological status of the animals and exhibits a pronounced growth stimulating effect, increasing the weight gain of pigs by 14.3%. In addition use of the preparation in rations of growing pigs has a normalizing effect on red blood and blood forming organs, increasing the number of red blood cells by 18.7%, hemoglobin - by 24.5%. Polisilar stimulates protein, carbohydrate and mineral exchanges, stabilizes the functional activity of the liver, reducing the toxic load on hepatocytes. Therefore, the preparation Polisilar has a pronounced biological and pharmacological activity and can be used in animal husbandry as an effective stimulant
151 kb

PROSPECTS FOR EXPANDING THE RANGE OF HEPATOPROTECTORS APPLICATION IN VETERINARY

abstract 1021408048 issue 102 pp. 779 – 789 31.10.2014 ru 619
This article presents the results of preclinical study of the pharmacological properties of a new medicine composed of phospholipids and antioxidants. It is found that the medicine called Gepavitol in experimental damage of the liver of laboratory rats shows some hepatoprotective effects
127 kb

RECEIVING FUNCTIONAL FEED ADDITIVE ON THE BASIS OF BENTONITE CLAYS AND CAROTENE CONTAINING RAW MATERIALS

abstract 0961402059 issue 96 pp. 841 – 851 28.02.2014 ru 644
In this article we have shown the results of studying of biologically active connections in bentonite clays, carotene containing raw materials for the purpose of receiving functional feed additive for agricultural birds
.