Regulatory-adaptive status of pregnant women with
diabetes should be considered at the solution of the
delivery
The research shows the possibility of extended
preimplantation genetic screening (PGD) that allows
to improve the strategy of selection of embryos that
satisfies not only the requirement of the absence of
chromosomal abnormalities, but also includes their
additional check for predisposition to various diseases,
as well as the choice of the embryo with the most
optimal HLA haplotype in cases with expressed
compatibility of parents for HLA-genes
The results of the questionnaire survey of cadets of
Maritime University, Maritime College and students
who had been given training in the Institution of
Advanced Training are presented. It is revealed that
the level of motivation of ship personnel for first aid
treatment to victims on commercial ships is two times
lower than that of cadets. The conclusion about the
necessity of solution the legal aspects of sailorsparamedics,
working under the Russian flag was made
Pathology of digestive organs is high on the list in
structure of diseases of children and teenagers. Now
many pediatricians face that teenagers at the same
time have several diseases. The most exact method of
detection of the available pathology is medical
examination. These inspections of rural teenagers with
chronic gastroenterological pathology are given in
article. The carried-out work allowed revealing the
main features of a state of health of this contingent
The dramatic lowering of intraocular pressure
(hypotony) is developing during glaucomatous surgery
due to the formation of the new aqueous humor
outflow. The calculations of the flow in the fluid
balance parameters have shown, that for the normal
intraocular pressure maintenance in the postoperative
period the fluid flow out of the anterior chamber
should not exceed 0,04 microliter in minute. The
intensity of the aqueous humor outflow through the
shunts with different parameters does not depend on
the shunt length. The shunt with the inner hole radius
0,025 mm is the most safe as it provide the less
outflow. The experimental comparative study of the
static viscosity of the most widely used viscoelastics in
ophthalmological surgery was carried out. It was stated
that used in eye surgery viscoelastics on the basis of
1%, 2% and 3% sodium hyaluronate possess the
viscosity, that differs in 10 and 100 times and has
significant influence on the flow intensity out of the
anterior chamber when the new outflow tracts are
formed. The mathematically based choice of the most
optimal relationship between the viscoelastics physical
parameters and the inner hole size of the shunt type
glaucoma drainage devices was established. Shunt
with the inner hole radius 0,05 mm and simultaneous
use of 2% and 3% sodium hyaluronate solution is the
most safe for the maintenance of the eye tonus during
the first 5 days after glaucoma surgery. The presented
correlation allows to increase the safety of the surgical
treatment of the patients with the refractory glaucoma
Isolation of fetal cells from the blood of a pregnant
woman is more relevant for receiving the information
of the genome of a fetus and implementation in clinical
practice, non-invasive screening methods for prenatal
diagnosis. The work proposes efficient ways of sorting
trophoblasts circulating in maternal blood for the
diagnosis of fetal aneuploidy in early gestation by
analyzing microsatellite marker of the chromosomes
that most prone to numerical aberrations (13, 18, 21, X
and Y). A set of microsatellite markers allowed to
reveal aneuploidy in three pregnant women, and also
to exclude mosaicism and contamination of samples
with maternal cells. A retrospective analysis of data on
invasive cytogenetic studies (chorionic villus
sampling) confirmed the results of the study
The aim of this work: a study of health - social and ethical aspects of health care workers in the framework of the prevention of a healthy lifestyle among youth. To study the level of students' knowledge about HIV prevention and detection of bad habits - drinking, smoking, drug addiction, a study author profiles. We
have used empirical, sociological and statistical methods
The article presents the evaluation of the lability of the visual analyzer among healthy individuals and patients with lesion after a stroke in the occipital cortex, temporal and parietal lobes
Uterine cancer is the sixth on prevalence of cancer
among women in developed countries. Hyper-estrogen
level by endogenous or exogenous origin plays the
leading role in this disease pathogenesis. This study
purpose was investigating the expression of genetic
loci responsible for the estrogen reception and
metabolism to better understanding of the molecular
mechanisms of uterine tissues malignancy. We
investigated the relative expression of genes (CYP1A
1, CYP1A 2, CYP1B 1, CYP19A, ESR1, ESR2, GPER,
STS, SULT1A and SULT1E1) by real-time PCR in
tumor and conditionally healthy uterine tissues of 27
female patients in Southern Russia aged 38-72 years
with histologically confirmed diagnosis of uterine
cancer. It is found that transcription activity of these
genes during malignancy of uterine tissues depends of
female patients age and the stage of tumor cells
differentiation. It is found that malignancy change in
the transcriptional activity of investigated genes in
uterine tissue depends of patients age and stage of
tumor cells differentiation. Particularly, it was found,
that changes of gene transcription balance of enzymes
that provide sulfation and hydrolysis of steroid sulfates is depending of patient age and the degree of tumor
cells differentiation. In addition, the sinking of gene
expression of nuclear estrogen receptor ESR1 as
lowering cell differentiation of tumor tissues. We have
also shown gene expression of nuclear estrogen
receptor ESR1 decline as lowering cell differentiation
of tumor tissues
The aim of the research is to study the peculiarities of
vaginal microbiocenosis in female patients with
metabolic syndrome during peri- and postmenopause.
320 women in the climacteric period aged of 45-70
were examined. Two groups were formed: the main
group (160 female patients with metabolic syndrome),
the control group (160 women without metabolic
syndrome). The average age of women 54.5 ± 7.2
years. Depending on the length of menopause each of
the two groups was divided into three
subgroups.Microscopy of vaginal smears, the
colpocytological analysis, the culture test of vaginal
discharge were conducted. The statistical processing of
the results was carried out with the help of programme
sets Microsoft Office 2010 (MicrosoftExcel) and
«STATISTICA® for Windows 6.0». A tendency of
decreasing frequency of non-specific vaginitis with
aging and of increasing frequency of vaginal atrophy,
disorders of vaginal biocenosis (lactobacillus
deficiency and the domination of conditionally
pathogenic microorganisms) was discovered. The
frequency of vaginal atrophy in women with a length
of postmenopause of 10 years and older was 65.9% in
the subgroup of in female patients with metabolic
syndrome and 63.6% in the subgroup of female
patients patients without it. The more observable
changes in vaginal biotope were found in women with
metabolic syndrome