The revolutionary discoveries of recent years in immunology has proved that protection from infections and biological aggression leading role played by innate immunity, which leads to the launch and subsequent work of specific adaptive immunity. Today, it is well-known that almost any pathology of the animal affects the immune system and creates an immune imbalance, leading to development of chronic pathological process, frequent relapses and to the development of different kind of complications. Secondary immunodeficiency states are widely distributed and differ in many etiological factors age, nutritional, medicinal, infectious and neoplastic nature, which leads to increased susceptibility of animal to various раthogenic factors, the weakening of the body. Awareness of the role of immunological disorders in the pathogenesis of a number of diseases has led to the need use in veterinary medicines that are aimed to influence on the immune system of the animal at the known molecular mechanism, to combine safety with high clinical efficacy. In this respect, a promising immunomodulators of microbial origin, due to the knowledge of the recognition mechanisms of the innate immune system such as bacteria as a whole, separate structural units, including mini-optimal biologically active fragments. This review is dedicated to one of the immunomodulator of microbial origin – which is an analog of biologically active fragment of muramyldipeptide of bacterial cell walls ‒ glucosaminylmuramildipeptide (GMDP), which is the active substance of registrated in Russia drug with the trade name Glicopin for use in veterinary practice. The drug showed high efficiency when used in cats, dogs, rodents, ferrets with infections of bacterial and viral etiology; cancer; with the aim of improving the natural resistance of the organism of young and old animals; enhance the effectiveness of vaccination in immunocompromised animals; postvaccine reduce complications; reduce stress financial position, such as during transportation and various veterinary treatments; injuries and on-line intervention (for stimulation of repair processes and tissue regeneration); prevention of immunodeficiency in newborn animals; the reduction of postpartum involutional processes in the uterus. Analysis of literature data allows us to consider an important outcome of immunologiс discoveries of recent years is the change of views on the question of the treatment of infectious diseases and the role of drugs as activators of innate immunity, among which an important role is played by a synthetic analogue of muramyldipeptide (GMDP) is a drug with a known molecular mechanism of action
The article deals with the migration and its creating
reasons, which have great role in changes of the content
and number of the population, the effects of migration
processes in the Nakhchivan Autonomous Republic on
demographic development and the problems of their
settlement. For this reason, the problems caused the
internal and the external migration of the population
from the beginning of independence years are analyzed.
Starting from the second decade of independence the
progress in the rising of natural and migration increase
of the population at the result of establishment of new
workplaces and industrial facilities are foregrounded
The transformation of society, its subsystems and
institutions led to the changing requirements of
professional competencies of graduates. Among the
most significant types of professional activities in
national standards research activities are called.
Accordingly, an important role in preparation of
graduating students of institutions is now played by
such form of independent work as research activity.
The article is devoted to the study of the influence of
scientific-research work of students on the formation
of their professional competences. It discusses the
concept of competence, research work of the student.
Presents the results carried out by the authors of the
sociological research devoted to the study of attitude
of students of Kuban state technological University for
the research work. The basic forms of research work
done by students are pointed. The ideas of respondents
about the role of scientific work in training and social
mobility of graduates are considered. Key qualities
and competencies that can be formed in the process of
employment of research work are certain. Among
them the most important the respondents believe the
skills of working with information, skills of selfeducation,
development of creative abilities
A study of the Russian costume and household
items was carried out. It is proved that folk art of
embroidery has deep artistic and craft traditions
and historical roots and is a special socio-cultural
type of folk culture. The ornaments were one of the
characteristic features of Russian clothing, its
technical techniques of embroidery, specific
ornamental motifs and colors, which determine its
originality, being, as it were, a passport of culture,
its historical path, intercultural and interethnic ties.
It is determined that decorative decoration with
embroidery of costume complexes, related to
archaism, is the value of Russian folk culture at
historical stages as universal values. The nature
and quantity of embroidery, even the semantic
meaning of ornamental patterns, depended on the
expediency, characteristic of folk clothes, on
reasons of economy, age and local differences, and
various customs in accordance with which clothes
were used. Images of ancient Slavic mythology
came into folk embroidery and lived there for
centuries not by chance. They decorated clothes,
towels, and ghosts, which had important ritual
significance during folk festivals and traditional
rituals. The people faithfully observed the laws of
fathers and grandfathers, along with them, from
generation to generation, images of ancient
mythology also came. The implication of the
research is that the history of every country entirely
depends on the artifacts which bear global
information about the epoch they were created
In the article, we consider climatic conditions during the cold period of the year in the mountain claster of
Sochi. We have analyzed variability of time series of
air temperature and precipitation sums at meteostation
Krasnaya Polyana. We have established, that average
daily temperature in the cold period was growing
during the last thirty years. This process was
accompanied by decreasing of daily temperature
amplitides. Winter of the year 2016/17 is characterized
by early beginning of snow accumulation because of
comparatively low temperatures in December 2016.
This was the reason in general for comparatively more
dense snow cover and to more frequent avalanches
One of the main components of quality of training of modern qualified personnel is the high level of teaching in universities. The article analyzes the problems of teaching information technology, preventing the formation of the high level of information competence in graduates of agricultural universities. This study examines the causes of problematic situations in teaching the subject: a low level of training of students on informatics and weak motivation of first-year students to study it; organizational and substantive errors of school and university education; low motivation of teachers to improve their professional level, to the publication of educational literature and creation of electronic materials; under-funding of personnel and hardware and software support of educational process; increasing the training of classroom teachers and number of subjects. The author proposes some approaches of a general nature to the solution of the problems under consideration: redistribution of the training course on the stages; main requirements of the school and University curriculum; raising the prestige of obtaining agricultural education and the introduction of entrance examinations for applicants; the introduction into the learning process of modern hardware and software technologies and new forms of education; reforming the system of professional development of teachers; the decline in classroom teachers; improving the system of material incentives for teachers to update the educational literature and the preparation of electronic materials; modernization of system of preparation of manuscripts for publication in the printing house; increase of salaries and introduction of allowances to teachers; improving the system of performance evaluation of teachers. Implementation of the proposed package of measures will lead, in the author's opinion, to increase the prestige of the teaching profession in society and the quality of teaching, thereby improve the degree of training of graduates of agricultural universities
The article reviews the results of studying the influence of mineral fertilizers on the uvological, yielding and qualitative indices of the Merlot grape variety in the Anapo-Taman zone of the Krasnodar region. The technology of cultivation of grapes on the experimental plot was performed in accordance with the accepted for the given zone and culture. Agrobiological work was carried out at the optimal time and had a high quality of execution. Grape bushes were laid in a 3.0 x 2.0 m pattern. Formation - a two-shoulder horizontal cordon. On the bushes, there was formed the same load shoots and bunches. Scheme of experience: option 1 – no fertilizers (control); option 2 - superphosphate with a mixture of potassium salt (P90K90) from the autumn; option 3 – nitroammofoska (N120P120K120) from autumn; option 4 – ammonium nitrate (N60) in early spring. Analysis of the results of the studies on the study of biological features of growth, fruiting, yield and quality of Merlot grape varieties on the background of the use of mineral fertilizers shows their high efficiency in the conditions of the Anapo-Tamanskaya zone of the Krasnodar region and can be recommended for use in production conditions. Autumn application of nitroammofoski (N120P120K120) provides an increase in yield by 68.3%, increases the yield of mash from a hectare by 76.7% and the collection of sugar by 97.6%. Autumn application of phosphate-potassium fertilizers (P90K90) and early spring application of ammonium nitrate (N60) also contributed to an increase in yields by 33.3 and 40.6%, respectively. On the output of the wort, these options are equal, and for the collection of sugar phosphate-potassium fertilizers exceed ammonia nitrate
The soil fertility increase issues are very relevant now. Intensive development of agriculture cannot be made effectively without complex actions for farmlands protection from different types of degradations. On the one hand, it is necessary to ensure the maximum harvest of crops, and to preserve and increase the fertility of the soil and prevent negative anthropogenic impact on the environment on the other. For an extended reproduction of soil fertility, a system of measures is necessary for introduction of mineral and organic fertilizers into the soil, agrotechnical and reclamation methods, stimulation of humus formation processes, and so on. Therefore, methods are important that allow us to estimate the planned measures in advance to improve soil fertility and to eliminate environmental damage. In the article, the estimated parameters are treated by random variables. This allows us to consider the uncertainty in terms of probability distributions. It is offered a probabilistic model of the process of reducing the price of the proposed activity. Mathematical expectation, variance, distribution density of the considered random variable probabilities as the main characteristics of the object state price are calculated. The model can be used to address issues of rational use of land, scientifically based land management organization, when drafting land reclamation project
The concept of generic polynomial appeared in
Saltman’s works at the end of the last century and it is
connected with the inverse problem of Galois theory,
which is still far from its complete solution. Let G be a
finite group and K be a field, the polynomial
f(x,t1, … , tn) with coefficients from the field K is
generic for the group G, if Galois group of this
polynomial over the field K(t1, … , tn) is isomorphic G
and if for any Galois extension L/K with Galois group
isomorphic G there are such values of parameters
ti
= ai
, i = 1,2, … , n, that the field L is the splitting
field of the polynomial f(x,a1, … , an) over K. Generic
polynomials over a given field K and a given finite
group G do not always exist, and if they exist then it’s
not easy to construct them. For example, for a cyclic
group of the eight order C8 there is no generic
polynomial over the field of rational numbers Q,
although there are found specific polynomials with
rational coefficients having Galois group isomorphic
C8. Therefore, this is of interest to construct generic
polynomials for the group G in cases when G is a
direct product of groups of lower orders. In this study
we show to solve this problem in case when G is a
direct product of certain cyclic groups and there is a
type of corresponding generic polynomials. Moreover,
we give constructions over the fields of characteristic 0
and over the fields of characteristic 2
A model is developed that describes the formation of the
plasma channel and the trace when moving in a
conducting medium of various objects that are sources of
plasma - ball lightning, plasmoids, charged particles, and
so on. To describe the contribution of conduction
currents, we modified the standard electrostatic equation
considering the vortex component of the electric field.
As a result of this generalization, a system of parabolictype
nonlinear equations is formulated that describes the
formation of the plasma channel and the track behind the
moving object. In this formulation, the problem of the
formation of the lightning channel in weak electric
fields, characteristic for atmospheric discharges of cloudearth,
is solved. Numerical simulation of the motion of
plasma sources in a region with a ratio of the sizes 1/100,
1/200 makes it possible to find the shape of the channel
and the total length of the track, as well as the branching
regimes. It was previously established that there are three
streamer branching mechanisms. The first mechanism is
associated with the instability of the front, which leads to
the separation of the head of the streamer into two parts.
The second mechanism is related to the instability of the
streamer in the base region, which leads to the branching
of the streamer with the formation of a large number of
lateral streamers closing the main channel of the
streamer to the cathode. The third branching mechanism,
observed in experiments, is associated with the closure
of the space charge to the anode through the streamer
system. These branching mechanisms are also revealed
when the leader is spread. Numerical experiments have
revealed a new channel branching mechanism and a
trace behind a moving plasma object, caused by the
conductivity of the medium