An impact analysis of abiotic factors of ecosystems on
the metabolic processes of the broiler chicken
organism under various methods of poultry operation
has been carried out. The analysis results confirm that
the enorganic biochemical processes are under the
influence of the environment, and any changes in its
condition cause the development of response reactions
of the organism at the biochemical level. The source of
control of the relative constancy of the milieu interieur
is the interaction of tropic and effector hormones.
Adrenocorticotropic hormone and cortisol are the main
hormones of adaptation. The activity of the adrenal
capsules turns to be an effector peripheral link of the
reflex chain of the adaptive reaction of the organism.
Adrenal hormones have a direct impact on tissue
metabolism. The following aspects have been taken
into consideration: technological growing conditions,
production parameters, morphological blood values of
chickens of different ages, quantitative content of
adrenocorticotropic hormone and corticoid in the
blood, morphology of the adrenal capsules. The
abiotic factors of the cage management system
contribute to an increase in the concentration of corticoid in the blood of broiler chickens, compared
with this value of the broilers grown under the floor
management
Study of dynamic sensitive of microorganisms shows wave shape change of characters with change of dominance with sensitive aminoglicozids and hinolone ftorhinolone groups of drugs
The article presents results of the study on the use of
associations of probiotic bacteria in black-and-white
breed calves. We have analyzed the effect of
associations of probiotic bacteria on hematological
(red blood cells and white blood cells, hemoglobin and
hematocrit) and blood biochemical parameters at
calves. It was found that the associations of strains of
Bifidobacterium bifidum DSM 20456, ATCC 29521,
and Enterococcus faecalis H22; Bifidobacterium
bifidum DSM 20456, ATCC 29521 and Enterococcus
faecium UDC 86 do not have significant changes in
the basic blood parameters of the animals, while
improving some of counts during their use
Carotenoid preparations are quite widely used in a health care, but in the veterinary and animal husbandry, their use is limited. In terms of livestock farms of the Krasnodar region and the Rostov region at the biochemical monitoring studies of the cattle blood the lack of carotene in the serum is revealed from 45 to 100 % of the samples. To study the biological function of carotenoid we used preparations, which are the oily solutions for injections: β-carotene (manufactured by FS 42-3867, which is produced from the biomass culture of the fungus Blakeslea trispora) and lycopene, emitted from plants. The cows in the test groups during the dry period and within two weeks after birth got carotenoid preparation subcutaneously at a dose of 10 ml per animal with an interval of 7 days. As a result, it was found out that the application of carotenoids has the most favorable conditions for the flow of labor and the postnatal period, which are manifested in the decrease in obstetric and gynecological diseases in cows and reduce the period of infertility. In the experimental groups the levels of vitamin A and carotene1,3 times higher (1,26 ± 0,14 μmol/L vs. 0,97 ± 0,09 μmol/L ) 1,8 times (0,34 ± 0 03 mg /% vs. 0.61 ± 0.11 mg /%) respectively in comparison with the parameters of the intact animals at a high level of confidence (P < 0,05). Phagocytic number and percentage of digestion of neutrophils increased by 8,5 %, the difference in the number of B-cells reached 9,1%, T-cells – 6,7%. In a humoral immunity found a significant increase in Ig A. After comparison of the level of lysozyme activity of blood serum was observed its reduction in all animals immediately after birth, but in the experimental groups this process was less pronounced. The use of carotene preparations helps to reduce the concentration of lipid peroxidation products in the body of cows (diene conjugates - by 16,6 %, ketodienes - by 35,7 %, malondialdehyde – by 11,3 %), which creates favorable conditions for the flow of the metabolic processes associated with ensuring the normal childbirth and post-partum involution of the genitals. In the group of cows, receiving the carotenoid lycopene, the dyspepsia morbidity of the newborn calves compared to a control decreased by 26,7 %, bronchopneumonia - by 13,3 %
An accelerated growth of farm animals in order to obtain maximum productivity is possible due to introduction stimulating additives and preparations based on them into the rations. One of such tools is Polisilar - complex preparation, which includes components that have a positive impact on various aspects of the animal metabolism in the conditions of physiological disorders. At the same time components of the preparation due to its high bioavailability exhibit a potentiating effect in the body that allows getting a more pronounced effect on its use. Studies were conducted on pigs 3-3.5 months age and showed that the Polisilar preparation has a positive effect on the clinical and physiological status of the animals and exhibits a pronounced growth stimulating effect, increasing the weight gain of pigs by 14.3%. In addition use of the preparation in rations of growing pigs has a normalizing effect on red blood and blood forming organs, increasing the number of red blood cells by 18.7%, hemoglobin - by 24.5%. Polisilar stimulates protein, carbohydrate and mineral exchanges, stabilizes the functional activity of the liver, reducing the toxic load on hepatocytes. Therefore, the preparation Polisilar has a pronounced biological and pharmacological activity and can be used in animal husbandry as an effective stimulant
In this study, the authors have defined the acute, subchronic and chronic toxicity of Uritosom preparation, and also its skin-irritating and sensitizing action. The studies that determined the acute toxicity of the drug Uritosom found that remedy which intended for the treatment and prevention of diseases of the genitourinary system with internal method of appointment during the entire observation period did not cause the death and acute toxicity in laboratory animals. In the study of subchronic and chronic toxicity of the drug Uritosom throughout the observation period in both experimental groups death and acute intoxication in animals not registered, also there were no negative phenomena in behavior, reflexes were saved. Consequently, the preparation according to the degree of impact on the body of warm-blooded animals refers to low-hazard substances (4th class of hazard according to GOST 12.1.007-76). Study of the irritant action of Uritosom preparation was carried out in two series of experiments. In the first series of experiments was determined irritating action by conjunctival swab sampling method, in the second - by skin application. The study of the sensitizing action of the drug was determined by the method of maximum sensitizing effects. The authors have found that the preparation has no irritating and sensitizing effect on the tissue in its application zone. On this basis, Uritosom preparation at different ways of application is low-toxic and it can be recommended for clinical research
Under conditions of white rats' hypothyroidism the
changes were studied in myeloid link of blood system
and corrective action of dalargin. It has been stated
that dalargin causes lasting leukopenia, short-time
eosinopenia with consequent normalization of their
number and momentarily stimulates neutrophilopoiesis
This article presents the results of testing the effectiveness of electrochemically-activated solutions of sodium chloride for disinfection of the facilities contaminated with highly pathogenic avian influenza
In the article data on spread of chronic endometritises
at cows are provided. The microflora range, being in
genitals of patients with a chronic endometritis of
cows is determined. We have developed a new drug
called Florinazol and we also determined his
antimicrobic and fungicide activity. Researches on
determination of acute and chronic toxicity, and also
irritant action on a mucous membrane of a uterus and a
vagina are conducted. Researches on studying of
influence of Florinazol on blood biochemistry at
rabbits are conducted. The optimum therapeutic dose
and frequency rate of its introduction is determined.
By results of researches it is established that 24,8% of
the cows containing on a farm with loose housing
content and 10,6% of cows on a farm with fastened
content have a chronic endometritis. At the same time
in uterus content in 84,3% of cases isolated
associations of bacteria and mushrooms in 65,2%, in
34,8% - monocultures of microorganisms. Offered by
us means the danger class belongs to substances lowdangerous
by the 4th. Doesn't possess irritant action,
doesn't exert a negative impact on blood biochemistry,
and also has outstanding therapeutic performance of
90% in case of its application in a dose of 100 ml
intra-vaginal at an interval of 48 hours
The opportunity of carrying out the accelerated indication of microbe contaminations of food products, food raw material and forages for animals with application of "VIDAS" immunological multiple parameter analyzer is investigated