The article deals with angiogenesis of squamous papillomas of dogs, which is a process of formation of blood vessels, providing neovascularization of tumors with their progression. The differentiation of papillomas depending on morphological and histological features was carried out, progressive and hyperkeratinized types were identified, which determine the stage of development and transition from one to another in the process of tumor growth. It is noted that with the progression of papillomas, the area of the constituent elements of the tumor increases, both due to the stroma and due to the parenchyma, but the stromal-parenchymal ratio changes in the direction of increasing the parenchymal component. Analysis of angiogenesis showed heterogeneity of the isolated vessels, both within the stromal component of papillomas, and depending on the type of tumors. There are three types of vessels – small, medium and large, there is a similar ratio of different types of vessels, regardless of the type of papillomas. Localization of vessels in the stroma depending on belonging to the selected species was studied. The total area of the section of blood vessels with cancer increases, and the ratio of the total area of the section of blood vessels to the area of the stroma is almost at the same level, which determines the dependence of the increase in the stromal component of papillomas from angiogenesis
The article is devoted to the method of selecting
quails. Intensive development of re-fishing requires the
development of breeding methods for selecting birds
and to carry out early predictions of egg production.
Targeted breeding selection is able to influence the
mechanisms of correlation dependencies between
individual parts of the animal's organism, significantly
change even firmly established interrelations, and
create new interactions more satisfying the needs of
the individual. The research task consisted of
establishing links between the parameters of the
skeleton and the productive qualities of the layers. The
studies were conducted on Texas white quails. We
took into account the live weight of the bird, the length
of the metatarsal and the third finger, as well as the
small and large diameters of the metatarsal.
Correlations were established between the length of
the pelvic limbs and the live weight of young quails
during growth. It is established that the growth of the
skeleton ends with the age of onset of puberty. This
provides a basis for predicting the live weight,
depending on the length of the pelvic extremities. It is
established that the live mass is directly related to the
egg productivity of quails. Thus, by selecting the birds
with the longest plus, it makes it possible for 25 weeks
of productivity to increase the egg laying on the initial
layer by 5,7 eggs and 6,2 eggs per average laying hen,
respectively
In this work, we have found shortened particle forms of the filamentous bacteriophage Pf, when the lysis of the Pseudomonas aeruginosa PAO1 strain was induced by extracts of bison feces to study the intestinal bacteriophages of this animal. The sizes of the shortened particles from 250 to 950 nm and their thickness 17 nm were determined. The particles had a slightly pointed one end and sometimes a flag on the other extended end. The particles were formed in the process lysis of this strain by other bacteriophages. These lysates also contained a high concentration of vesicles from the pseudomonad membrane. The article discusses the mechanisms of prophage induction in the Pseudomonas aeruginosa PAO1 strain due to phage-phage induction and substances of the investigated extract
The article deals with the similarity and difference of nosological images in veterinary medicine using a new method of agglomerative clustering implemented in Automated system-cognitive analysis (ASC-analysis) on a small numerical example. This method is called Agglomerative cognitive clustering. This method differs from the known traditional facts: a) parameters of a generalized image of the cluster are computed not as averages from the original objects (classes) or their center of gravity, and are defined using the same underlying cognitive operations of ASC-analysis, which is used for the formation of generalized images of the classes on the basis of examples of objects and which is really correct and provides a synthesis; b) as a criterion of similarity we do not use Euclidean distance or its variants, and the integral criterion of non-metric nature: "the total amount of information", the use of which is theoretically correct and gives good results in non-orthonormal spaces, which are usually found in practice; c) cluster analysis is not based on the original variables, matrices of frequency or a matrix of similarities (differences) dependent on the measurement units of the axes, and in the cognitive space in which all the axes (descriptive scales) use the same unit of measurement: the quantity of information, and therefore, the clustering results do not depend on the original units of measurement features. All this makes it possible to obtain clustering results that are understandable to specialists and can be interpreted in a meaningful way that is in line with experts' assessments, their experience and intuitive expectations, which is often a problem for classical clustering methods
Providing the population with basic food products, sources of proteins, fats, carbohydrates, vitamins and other essential nutrients is one of the main issues of ensuring the security of the country, while the requirement for food safety is paramount. Production of feed additives (concentrates), which improve feed conversion, while being natural and safe for animal health, acquires the greatest importance in the conditions of intensification of agriculture and increasing the competitiveness of livestock farms. Probiotic microflora, which, in competition with pathogenic, displaces the latter from the gastrointestinal tract, can be considered as one of the effective methods of controlling undesirable microflora in the digestive tract. In world science, research is actively conducted in the direction of searching for effective probiotic cultures. A promising way to increase the effectiveness of the use of probiotic feed additives is their addition to prebiotics, for example, including vitamins (antioxidants) and mineral substances (selenium). The purpose of this work was to determine the optimal ratio of biologically active substances contained in the feed vitamin-mineral concentrate, and probiotic microflora contained in the feed probiotic additive Bacell-M, for the development of complex feed concentrate. Using the Harrington's desirability function, the optimum ratio of biologically active substances and probiotic microflora in the recipe of the complex feed concentrate is determined, ensuring the maximum reduction in the serum levels of alanine aminotransferase in the blood serum of experimental animals, which characterizes the normalization of barrier organs
The article represents the results of studying the spatial-dynamic factors and revealing the regularities of the global spread of Lumpy skin disease in cattle. The developed risk analysis and epizootological forecast provides the keeping up with a multi-year trend for the growth of epizootic tension in this disease for the period up to 2030. The highest probability of disease registration from 0.6 to 1.0 is predicted for the tropical agroecosystems of the African continent (enzootic zone) in 2018-2030. There is a real risk of disease in neighboring countries of Eurasia with the probability is less than 0.4. In the Russian Federation, outbreaks can occur in all federal districts of the country, but the highest probability of its occurrence is possible in agroecosystems of the subtropics of the North Caucasus and Southern Federal Districts of the country
The article discusses the impact of color lighting on changes in productivity and environmental safety of poultry products. We have given recommendations to optimize the cost of electricity for lighting the house
The main diseases of lactating cows occur in the first
two months of lactation, i.e. during the production
peak of productivity. They are caused by the changes
in metabolism during the transition period, which are
not supported by adequate changes in the organization
of feeding, or rather sufficient to ensure cows with
nutrients, which causes a number of closely related
diseases. To allocate any of them is not possible, as
their manifestation depends on a number of reasons,
and depending on situation may prevail one or the
other. Among the most common diseases, there are
ketosis, milk fever (paresis of maternity), dysplasia of
the abomasum, acidosis, mastitis, endometritis,
laminitis and leukemia. These diseases cause the
greatest problems in herds with high productivity, and
are caused by changes in metabolism in cows in the
transition period and the inability to properly feed the
animals at this time. To identify the causes of these
diseases we do not need to study each of them
individually - it is enough to deal with the peculiarities
of metabolism. This period includes the month before
calving and the first or second month of lactation, but
the most important are 3 weeks before calving and 3
weeks later. In order to prevent metabolic disorders
there were developed and tested feed for feeding cows
before calving and immediately after calving. Their
effect was studied on milk production and health status
The article presents a factorial model for determining the needs of lactating cows in essential amino acids. The algorithm of the model uses fragments from the NRC – 2001 models [39], CNCPS – 200 [60], and research materials published in the world literature. Instead of the transformation coefficients of the metabolizable lysine and methionine for milk production equal to 0.85 and 1.00, respectively, by the CNCPS, the coefficients 0.68 and 0.66 were used according to Doepel et al., 2004 [49] and the authors' own data [69]. Norms obtained using this model in lysine and methionine in milk production and maintenance in percentage of metabolizable protein (MP) were 7.28 and 2.4%, which is identical to the NRC – 2001 standards, equal to 7.2 and 2.4 % respectively, obtained by dose – response method based on dozens of experiments. The norm of histidine was 3.5%, which closely corresponds to the indicator of 2.4 and 2.7 % MP [74], obtained by the incremental addition method. This indicates that the presented model is distinguished by sufficiently high accuracy and is comparable with the models developed by the dose – response method. However, the determination of the need of cows for amino acids in this model is much less expensive than the dose – response method. The need for the absolute amount of metabolizable essential amino acids (MEAA) for milk production (35 kg/d, yield milk protein 1103 gytt6) and maintenance cow - 600 kg, g/d: lysine - 178, methionine - 59, arginine - 119, histidine - 60, isoleucine - 138, leucine - 248, phenylalanine - 152, threonine - 134, tryptophan - 38, valine - 174; the need for only milk production, g/d: 130; 42; 81; 42; 95; 175; 98; 74; 25; 112; the need for only maintenance, g/d: 50; 16; 38; 20; 43; 73; 54; 60; 14; 64; the need for 1 kg of milk (31.5 g of protein) g/kg: 3.7; 1.2; 2.3; 1.2; 2.7; 5.0; 2.8; 2.1; 0.7; 3.2; need to maintain, g / kg 0.75: 0.41; 0.14; 0.31; 0.16; 0.35; 0.60; 0.44; 0.50; 0.11; 0.53. In addition, the article presents the norms of amino acids per 1 kg of dry matter (DM) ration. However, the proposed standards need a comprehensive assessment in the research and practice of dairy farming. Research is needed to improve the models and predict the MEAA in the rations in the following areas: studying the metabolism of amino acids in the body of cows and determining their costs for maintaining the digestive tract, tissues and organs, refining, on this basis, the utilization of amino acids for milk protein production and maintenance; the development of ideal amino-acid profile of low-protein diets, both due to the adjustment of natural ingredients, and through the use of amino acid preparations that are protected from disintegration in the rumen
Smallpox of turkey is a viral, slowly extending disease. It pathogenetically proceeds in a dermatotropic way, skin lesions are characterized primarily by two signs or focal necrotic focus centers or diphtheritic inflammation of mucous membranes, often of the upper respiratory tract. Etiological factor in smallpox are dermatotropic epitheliogenic viruses, the family of Avipoxvirus of Poxviridae. The purpose of this work was studying the features of clinic and the pathomorphological changes at smallpox at turkeys in the context of diagnostics methods and also generalization of treatment-and-prophylactic actions at this pathology. The diseased bird is the main source of infection. In addition, the smallpox virus particles can be spread by people providing care for the birds, indoor air, food, bedding material, excrement. Diagnosis of smallpox takes into account the symptoms; if an autopsy was performed, the result of a pathological pattern as well. Additionally, we can conduct a research of histological sections. Confirmation of diagnosis can be performed by a virological study and the blood serum. In accordance with the pathogenesis of smallpox, there is a classic skin form and diphtheritic. There may be a combination of the above manifestations of smallpox, therefore we can record the mixed form, in some cases, it may be atypical. Pathoanatomical changes come down to defeat a respiratory system of bodies, the upper airways, at the complicated forms there may be noted lesions in the internal organs. Laboratory methods include identification of the virus in the pathological material, as well as additional histological and virological studies using chicken embryos and bioassays. Treatment is difficult and not always effective. The main preventive measure against smallpox in turkey is vaccination, basic applied biologics are: Avivac-pox" strain "K", "Ospovat, Vectorman FP-MG". Prevention of smallpox includes the implementation of general veterinary and sanitary rules in conjunction with the mandatory special prevention. When planning measures to prevent the spread of smallpox, conditions are created to eliminate pathways of transmission of the pathogen – disinfection, disinsection and deratization, as well as vaccination of all susceptible livestock